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A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

EtG in hair can help detect alcohol use but may be inaccurate in people with certain health conditions.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

The model and estimator can predict drug exposure in kidney transplant patients well.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Certain vitamins in wrong amounts, alcohol abuse, metals, and other toxins can cause serious brain and nerve damage.

Different enzymes are active in different parts of developing mouse organs.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

Zinc levels in body fluids can help diagnose zinc deficiency in lambs, with fecal zinc as an early indicator.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Found different proteins in balding and non-balding cells, giving insight into hair loss causes.

Zinc is important for growth and health in animals, plants, and humans, and not having enough can cause various problems.

The right amount of retinoic acid is essential for normal hair growth and development.

Scientists can use engineered microbes to make L-aspartate and related chemicals, but there's still room to improve their efficiency.

Not getting enough minerals can lead to health problems and shorter lifespans.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Male hormones worsen kidney transplant damage, but blocking them helps.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Finasteride causes harmful organ changes in female mice.

Microneedle made of iron oxide and PVA helps hair regrowth in alopecia treatment.