research Advanced Inhibition of Undesired Human Hair Growth by PPARγ Modulation
GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.
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research Epithelial Cells in the Hair Follicle Bulge Do Not Contribute to Epidermal Regeneration After Glucocorticoid-Induced Cutaneous Atrophy
Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.
research Reduced Cell Cohesiveness of Outgrowths from Eccrine Sweat Glands Delays Wound Closure in Elderly Skin
Older people's sweat glands are less effective at helping skin wounds heal due to weaker cell connections.
research Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function
Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
research Epidermal Stem Cell Fate: What Can We Learn from Embryonic Stem Cells?
Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.
research Stimulation of Elastin Expression by Minoxidil in Chick Skin Fibroblasts
Minoxidil boosts elastin production, potentially helping skin diseases.
research Regional Difference in Sebum Production by Androgen Susceptibility in Human Facial Skin
The T-zone on the face has more androgen receptors and produces more oil than the U-zone.
research Enrichment and Characterization of Human Dermal Stem/Progenitor Cells Using Collagen Type IV
Scientists identified a group of human skin cells with high growth and regeneration potential.
research Topical Adenosine Increases the Proportion of Thick Hair in Caucasian Men With Androgenetic Alopecia
Adenosine treatment thickens hair in Caucasian men with hair loss.
research Progranulin, A Secreted Tumorigenesis And Dementia-Related Factor, Regulates Mouse Hair Growth
Progranulin overexpression leads to shorter, thinner hair and increased cell death in mouse hair follicles.
research Rapid Genetic Analysis of Epithelial-Mesenchymal Signaling During Hair Regeneration
The method quickly analyzes hair growth genes and shows that blocking Smo in skin cells stops hair growth.
research Isolation and Characterization of Cutaneous Epithelial Stem Cells
Scientists found ways to identify and collect skin stem cells, which vary by skin area and are delicate.
research Formation of the Cornified Envelope
The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.
research Role of Diet in Acne
Eating nuts, chocolate candy, and red tea might worsen acne, while eating more fresh vegetables could reduce it.
research Rac-Dependent Signaling from Keratinocytes Promotes Differentiation of Intradermal White Adipocytes
Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.
research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Attenuates the Adverse Effects of Glucocorticoids on Dermal Papilla Cells
Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.
research CCL5 Affects the Hair-Inductive Capacity of Three-Dimensional Cultured Dermal Papilla Cells
CCL5 is important for the hair growth potential of human dermal papilla cells.
research STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction, Hair Follicle Regeneration, and Wound Healing
Activating STAT5 in the skin's dermal papilla is key for starting hair growth, regenerating hair follicles, and healing wounds.
research Woolly Antics Between the Sheaths
Lipase H is important for hair follicle function and shaping hair fibers.
research The Hair Follicle Stem Cell As The Paradigm Multipotent Adult Stem Cell
Hair follicle stem cells can turn into many cell types and may help repair nerve damage and have other medical uses.
research Cell Death as an Architect of Adult Skin Stem Cell Niches
Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
research Implanted Hair-Follicle-Associated Pluripotent Stem Cells Aid Wound Healing and Reduce Scarring in Mice
Implanted special stem cells from hair follicles helped heal wounds faster and with less scarring in mice.
research Nestin as a Marker of Unipotent Epithelial Progenitor Cells Differentiating into Outer Root Sheath Keratinocytes in Embryonic and Adult Hair Follicles
Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.
research Nestin as a Marker of Unipotent Epithelial Progenitor Cell Differentiation into Outer Root Sheath Keratinocytes in Embryonic and Adult Hair Follicles
Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.
research Hypoxia Induced Multipotent Stem Cell-Secreted Proteins Induce Hair Growth in a Phase 1a/2b Trial in Male Pattern Baldness
A trial showed that a new treatment is safe and effective for male pattern baldness, with most participants growing new hair.
research The Editor's Choice: Summary of Studies on Skin and Hair Conditions
UV radiation may cause DNA changes in skin, certain UVB therapy helps psoriasis, a new gene mutation is linked to mild piebaldism, different immune cells affect psoriasis, a drug promotes hair growth, and some cancer drugs could treat skin barrier issues.
research Expression Patterns of the Siah Genes in Postnatal Mouse Skin
The Siah1 and Siah2 genes are active in mouse skin development and hair growth, especially right after birth.
research Tissue and Circulating MicroRNA Co-Expression Analysis Reveals Potential Involvement of miRNAs in the Pathobiology of Frontal Fibrosing Alopecia
Certain miRNAs might be involved in a hair loss condition called frontal fibrosing alopecia and could possibly help in its diagnosis.
research Immunohistochemical Insight Into the Association Between the Collapse of Immune Privilege in the Sweat Gland and Syringotropic Immune Cell Infiltrates in Collagen Diseases
The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.
research Establishment and Characterization of Human Sebocytic Progenitor Cells That Can Differentiate Into Functional Sebocytes
Researchers created human cells that can turn into sebocytes, which may help study and treat skin conditions like acne.