Corrections to 'Female Pattern Hair Loss and Its Relationship to Permanent/Cicatricial Alopecia: A New Perspective'

    Image of study
    TLDR Title change to "Central Centrifugal Cicatricial Alopecia (CCCA)"; common in African American women; hair-grooming methods may contribute; no effective therapy found; trials needed.
    This document is a correction to a previous publication about female pattern hair loss and its relationship to permanent/cicatricial alopecia. The correction includes a change in the section title from "Central Center CCCA" to "Central Centrifugal Cicatricial Alopecia (CCCA)" and provides a description of CCCA, which is a common type of hair loss that occurs almost exclusively in African Americans, particularly women. The document also suggests that hair-grooming methods specific to the African-American culture, such as hot combs, relaxers, tight braids, heavy extensions, and a variety of oils and pomades, could cause or contribute to the hair loss. No effective therapy for CCCA has been identified, and well-controlled clinical trials are needed to address these issues. The document also discusses the possibility that women with CCCA could have underlying female pattern hair loss, and a controlled trial of anti-androgens or 5% inhibitors early in the process may be of value to help sort out whether there is any androgen relationship to this process.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  121 upvotes 2 weeks ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 3 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

      community Can we get a reality check on PP405?

      in Research/Science  76 upvotes 2 weeks ago
      PP405 is a promising hair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.

    Related Research

    6 / 6 results