research The Hair Follicle as an Estrogen Target and Source
Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
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research Laminin-511 Is an Epithelial Message Promoting Dermal Papilla Development and Function During Early Hair Morphogenesis
Laminin-511 is crucial for early hair growth and maintaining important hair development signals.
research A Function for Rac1 in the Terminal Differentiation and Pigmentation of Hair
Rac1 is essential for proper hair structure and color.
research Multi-Potentiality of a New Immortalized Epithelial Stem Cell Line Derived from Human Hair Follicles
Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.
research Heparan Sulfate Regulates Hair Follicle and Sebaceous Gland Morphogenesis and Homeostasis
Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
research The Cellular Basis of Mechanosensory Merkel-Cell Innervation During Development
BMP signaling is essential for the development of touch domes.
research The Developmental and Molecular Requirements for Ensuring That Human Pluripotent Stem Cell-Derived Hair Follicle Bulge Stem Cells Have Acquired Competence for Hair Follicle Generation Following Transplantation
Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.
research Pharmacological Activation of Estrogen Receptors-α and -β Differentially Modulates Keratinocyte Differentiation with Functional Impact on Wound Healing
Activating ER-β, not ER-α, improves skin cell growth and wound healing.
research Blackcurrant Extract with Phytoestrogen Activity Alleviates Hair Loss in Ovariectomized Rats
Blackcurrant extract may help reduce hair loss by promoting stem cell activity in hair follicles.
research Stem Cells in the Body
Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.
research Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch+/- Mice
Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.
research SOX2 in the Skin: Roles in Biology and Pathology
SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
research Multi-Scale Spatial Mapping of Cell Populations Across Anatomical Sites in Healthy Human Skin and Basal Cell Carcinoma
The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
research Advances in Hair Diseases
The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.
research Mature Adipocytes Inhibit the Antimicrobial Function of Dermal Adipogenic Stem Cells: An Explanation for Impaired Cutaneous Defense in Obesity
Obesity can weaken the skin's ability to fight infections because fat cells stop and reduce the infection-fighting properties of nearby stem cells.
research The Anti-Apoptotic Bcl-2 Protein Regulates Hair Follicle Stem Cell Function
The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.
research The Rho Guanosine Nucleotide Exchange Factors Vav2 And Vav3 Modulate Epidermal Stem Cell Function
Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
research Cornification
Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.
research First Symposium on Natural Gene Therapy of the Skin
Natural gene therapy shows promise for treating skin disorders like epidermolysis bullosa.
research Stem Cells in Tissue Engineering
Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.
research Genetically Induced Cell Death in Bulge Stem Cells Reveals Their Redundancy for Hair and Epidermal Regeneration
Hair and skin can regenerate without bulge stem cells due to other compensating cells.
research Cell Death by Cornification
Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
research Dermal Wnt/β-Catenin Activation Tunably Controls Hair Follicle Initiation
Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.
research Divergent Proliferation Patterns of Distinct Human Hair Follicle Epithelial Progenitor Niches In Situ and Their Differential Responsiveness to Prostaglandin D2
Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.
research Long-Term Expansion and Differentiation of Adult Murine Epidermal Stem Cells in 3D Organoid Cultures
A new 3D culture system helps grow and study mouse skin stem cells for a long time.
research Distinct Stem Cells Contribute to Mammary Gland Development and Maintenance
Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin
The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
research Elevated Ornithine Decarboxylase Activity Promotes Skin Tumorigenesis by Stimulating the Recruitment of Bulge Stem Cells but Not via Toxic Polyamine Catabolic Metabolites
Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
research Activation of Nrf2 in Keratinocytes Causes Chloracne-Like Skin Disease in Mice
Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
research Dual-Action Icariin-Containing Thermosensitive Hydrogel for Wound Macrophage Polarization and Hair Follicle Neogenesis
The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.