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The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Nerves and chemicals in the body can affect hair growth and loss.

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Hair follicle regeneration needs special conditions and young cells.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Hair shedding is an active process that could be targeted to treat hair loss.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

Tiny needles with valproic acid can effectively regrow hair.

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Notch-related genes play a key role in the development and cycling of hair follicles.

PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.

Apoptosis is crucial for healthy skin and treating skin diseases.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

MicroRNAs are crucial for controlling skin development and healing by regulating genes.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Endo-HSE helps grow hair-like structures from human skin cells in the lab.