1 citations
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November 2024 in “Diabetes Metabolic Syndrome and Obesity” In this study, researchers found that a specific genetic variant in the INSR gene is linked to severe insulin resistance and hyperandrogenemia in type A insulin resistance syndrome, suggesting the benefit of exon sequencing for accurate diagnosis and treatment.
1 citations
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August 2024 in “Transgenic Research” In this study, the researchers observed that inducing and then withdrawing β-catenin expression in a bigenic mouse model caused reversible changes in skin morphology, indicating dependence on β-catenin signaling.
1 citations
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January 2024 in “Nature communications” This study found that stimulating toll-like receptor 5 via mucosal delivery of a flagellin-containing fusion protein effectively extended lifespan and enhanced healthspan in mice, including improved bone density and cognitive capacity.
1 citations
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January 2024 in “Theranostics” This source reviews the role of exosomes in regenerative medicine, highlighting their ability to mediate cell communication and transport biomolecules to enhance or impair biological functions, with potential applications in tissue repair and regeneration.
1 citations
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October 2023 in “Life science alliance” This study observed that pantethine, a vitamin B5 precursor, attenuates tumor growth in immunocompetent mice by enhancing antitumor immunity, but its effect is limited by immune cell exhaustion over time.
1 citations
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July 2023 in “Nature communications” This study found that deleting the Mof gene in mouse skin leads to severe defects in skin cell self-renewal, differentiation, and hair follicle growth, indicating that MOF is crucial for mitochondrial and ciliary gene expression and essential for skin development.
1 citations
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April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study is the first to document alopecia in Guadalupe fur seals in the Northeast Pacific Ocean, finding that it may result from nutritional stress due to higher sea surface temperatures.
1 citations
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April 2023 in “Clinical, cosmetic and investigational dermatology” This study reviewed existing literature and reported two cases of perinevoid alopecia, suggesting that melanocyte antigens may be involved in its development.
1 citations
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March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that AtCEPs in Arabidopsis thaliana play a role in controlling root hair growth by processing EXT proteins, with NAC1 acting to regulate their expression and influence elongation.
1 citations
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December 2022 in “Türk tarım - gıda bilim ve teknoloji dergisi” This review discusses the diversification of tea products and their associated health benefits, highlighting the economic challenges faced by tea-producing countries and the global marketing strategies of the tea industry, but reports no new experimental findings.
1 citations
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January 2022 in “Pharmaceutical Sciences Asia” This review highlights the potential of microneedles as a low-cost, well-tolerated method for transdermal drug delivery in dermatology, though further research is needed to establish their clinical efficacy.
1 citations
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August 2019 in “Research Square (Research Square)” In this study, researchers found that the cashmere hair growth cycle is divided into three periods and key genes like KAP and KRTAP are positively correlated with these cycles in cashmere goats.
1 citations
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October 2018 in “InTech eBooks” This article reviews treatment approaches for cicatricial alopecia, describing how medication efficacy varies and suggesting autologous hair transplantation for stable cases; no new clinical data are presented.
1 citations
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November 2017 in “Expert opinion on orphan drugs” This review discusses the genetic basis of ectodermal dysplasia, highlighting that identification of gene pathologies enhances diagnosis and supports prenatal DNA testing, but it reports no new clinical results.
1 citations
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January 2013 in “Springer eBooks” Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.
1 citations
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May 2009 in “Wiley-Blackwell eBooks” Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.
1 citations
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May 2006 in “Expert Opinion on Therapeutic Patents” This review summarizes 19 patents filed since 2000 for treating or preventing chemotherapy-induced alopecia, but reports no new clinical findings.
1 citations
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August 2000 in “Expert Opinion on Therapeutic Patents” This article reviews the therapeutic use of carnitine derivatives for re-establishing mitochondrial functionality in aging and reports no new clinical results.
1 citations
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July 2024 in “International Journal of Biological Research” This study found that a high percentage of pediatric sickle cell disease patients have parents from medium-high socioeconomic status, indicating that the educational background of parents did not influence the disease's prevalence.
1 citations
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January 2023 in “Bioscience Journal” This study found that combining sorafenib with Platycladus orientalis leaf extract effectively suppressed cervical cancer cell growth by increasing tumor suppressor gene expression and reducing anti-apoptotic gene expression, suggesting a potential rationale for further clinical trials.
1 citations
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June 2017 in “International Journal of Toxicology” This symposium reviewed strategies to advance stalled drug molecules, discussed common regulatory hurdles, and explored options for repurposing drugs, but it reported no new research findings.
1 citations
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May 2017 in “InTech eBooks” This chapter reviews signaling pathways related to androgenic alopecia in dermal papilla cells of balding human scalps, integrating published information and analysis of molecular interactions, without reporting new clinical results.
1 citations
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January 2017 in “Springer eBooks” This review discusses the role of flavonoids and Nod factors in the symbiosis between legumes and rhizobia and reports no new results; the authors argue this knowledge could enhance sustainable agriculture.
This study found that Plakophilin 1 regulates innate immune responses in keratinocytes by controlling RNA helicase activity, balancing inflammation during epidermal immune challenges.
This study utilized a pigmented human epidermal equivalent model to incorporate melanocytes into the epidermis and found enhanced differentiation potential compared to conventional in vitro systems, reflecting in vivo cellular trajectories and highlighting melanocyte-to-keratinocyte communication pathways.
July 2026 in “International Journal of Drug Delivery Technology” This study found that a combination of curcumin and piperine demonstrated moderate antioxidant activity, negligible cytotoxicity, and significant potential for promoting hair regrowth in rat models of alopecia, suggesting it could be a safe and effective natural alternative for managing hair loss.
July 2026 in “Nature Communications” In this study, researchers used patient-derived organoids to model metastasis in colorectal cancer and discovered that cancer cells temporarily switch to a wound-healing program, orchestrated by reduced EZH2 activity and YAP signaling, before spreading to new organs.
July 2026 in “Pharmacological Reports” In this pilot study, topical latanoprost acid was observed to increase hair count and improve hair follicle structure in women with androgenetic alopecia, with no serious adverse events, suggesting potential for further investigation to confirm its efficacy and safety.
July 2026 in “Discover Food” This review critically examines scientific evidence on the health benefits of rosemary bioactives, finding potential in managing age-related diseases and skin aging conditions, and discusses their application in functional foods and aromatherapy, along with associated safety concerns.
In this study, Neeli Bhringadi hair oil showed statistically significant improvements in hair growth rate, density, thickness, and reduction in premature graying on participants with androgenetic alopecia and hair graying over 120 days, supporting its potential use in integrative hair care.