Perinevoid Alopecia: Report of Two Cases and Literature Review

April 2023 in “ Clinical, cosmetic and investigational dermatology ”

Yujing Zhang, Jianzhong Zhang, Cheng Zhou

perinevoid alopecia alopecia areata pigmented nevus halo nevus melanocytes

TLDR Antigens from skin cells may cause hair loss in perinevoid alopecia.

Perinevoid alopecia (PA) is a rare form of alopecia areata (AA) linked to a central pigmented nevus. This study presented two new cases and reviewed 14 cases from 11 previous studies. One case uniquely combined PA with a halo nevus and spared white terminal hairs in the hair loss area, a rare occurrence. The findings suggest that antigens from melanocytes may play a role in the development of AA in PA.

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Semantic ratio: 80%