TLDR Antigens from skin cells may cause hair loss in perinevoid alopecia.
Perinevoid alopecia (PA) is a rare form of alopecia areata (AA) linked to a central pigmented nevus. This study presented two new cases and reviewed 14 cases from 11 previous studies. One case uniquely combined PA with a halo nevus and spared white terminal hairs in the hair loss area, a rare occurrence. The findings suggest that antigens from melanocytes may play a role in the development of AA in PA.
Cited in this study
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290 citations
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January 2018 in “Journal of The American Academy of Dermatology” Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.
3 citations
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June 2013 in “The American Journal of Dermatopathology” A man with a birthmark on his scalp developed hair loss that improved with treatment, but the link between the birthmark and hair loss was unclear.
148 citations
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March 2019 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
4 citations
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November 2018 in “JAAD case reports” Alopecia areata can sometimes appear as a straight line of hair loss instead of round patches.
May 2018 in “Journal of cosmetology & trichology” Combining platelet-rich plasma therapy with prostaglandin-F eye drops can significantly regrow hair in alopecia universalis.
