TLDR Antigens from skin cells may cause hair loss in perinevoid alopecia.
Perinevoid alopecia (PA) is a rare form of alopecia areata (AA) linked to a central pigmented nevus. This study presented two new cases and reviewed 14 cases from 11 previous studies. One case uniquely combined PA with a halo nevus and spared white terminal hairs in the hair loss area, a rare occurrence. The findings suggest that antigens from melanocytes may play a role in the development of AA in PA.
290 citations,
December 2017 in “Journal of The American Academy of Dermatology” Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.
3 citations,
August 2012 in “The American Journal of Dermatopathology” A man with a birthmark on his scalp developed hair loss that improved with treatment, but the link between the birthmark and hair loss was unclear.
148 citations,
December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
4 citations,
November 2018 in “JAAD case reports” Alopecia areata can sometimes appear as a straight line of hair loss instead of round patches.
May 2018 in “Journal of cosmetology & trichology” Combining platelet-rich plasma therapy with prostaglandin-F eye drops can significantly regrow hair in alopecia universalis.
