Perinevoid Alopecia: Report of Two Cases and Literature Review

April 2023 in “ Clinical, cosmetic and investigational dermatology ”

Yujing Zhang, Jianzhong Zhang, Cheng Zhou

perinevoid alopecia alopecia areata pigmented nevus halo nevus melanocytes

Studysummary This study reviewed existing literature and reported two cases of perinevoid alopecia, suggesting that melanocyte antigens may be involved in its development.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

Perinevoid alopecia (PA) is a rare form of alopecia areata (AA) linked to a central pigmented nevus. This study presented two new cases and reviewed 14 cases from 11 previous studies. One case uniquely combined PA with a halo nevus and spared white terminal hairs in the hair loss area, a rare occurrence. The findings suggest that antigens from melanocytes may play a role in the development of AA in PA.

View this study on dovepress.com →

Discuss this study in the Community →

Research cited in this study

4 / 4 results

research Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management

290 citations , August 2021 in “Clinical Reviews in Allergy & Immunology”

JAK inhibitors show promise for treating alopecia areata, but more research is needed.

research Alopecia Areata: Overview and Insights from January 2018

290 citations , December 2017 in “Journal of The American Academy of Dermatology”

This article reviews the epidemiology, clinical evaluation, and pathogenesis of alopecia areata and highlights recent advancements, but it does not report new clinical findings.

research Congenital Combined Melanocytic Nevus of the Scalp With Associated Alopecia Areata

3 citations , August 2012 in “The American Journal of Dermatopathology”

This report describes a 20-year-old Chinese man with a rare combination of congenital compound and blue melanocytic nevus associated with alopecia areata.

research Coexistence of Giant Blue Nevus of the Scalp with Hair Loss and Alopecia Areata

3 citations , November 2010 in “The Journal of Dermatology”

This case report details a rare instance of a giant cellular blue nevus on the scalp, highlighting its potential to damage underlying bone and hair follicles, alongside a separate alopecia areata lesion successfully treated with topical corticosteroid.