Congenital Combined Melanocytic Nevus of the Scalp With Associated Alopecia Areata

    August 2012 in “ The American Journal of Dermatopathology ”
    Yee‐Kiat Heng, See Ket Ng, Kong-Bing Tan, Joyce Siong‐See Lee
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    TLDR A man with a birthmark on his scalp developed hair loss that improved with treatment, but the link between the birthmark and hair loss was unclear.
    In 2013, a case study described a 20-year-old Chinese man with Marfan syndrome who experienced hair loss over parts of his scalp, where a blue-gray plaque was also observed. He developed alopecia areata (AA) in two patches, which improved with steroid injections. A biopsy confirmed a congenital combined melanocytic nevus without signs of AA, but the nevus was too large to remove. This case was unusual because the alopecia associated with the nevus appeared when the patient was 19, rather than at birth. The relationship between the melanocytic lesion and AA was investigated but remained inconclusive. The study emphasized the need to differentiate between combined melanocytic nevus and neurocristic hamartoma due to their similar appearance but different outcomes.
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