2 citations
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June 2024 in “Advanced Healthcare Materials” In this study, researchers highlighted the integration of computational technology with nanozyme research, enabling atomic-level kinetic analysis and improved design and synthesis of nanozymes, while enhancing detection methods through automated, accurate, and reproducible analyses.
August 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” This study developed the CATNIP computational model, which uses biological and chemical information to successfully identify drug repurposing opportunities for various conditions, including Parkinson’s disease and Type 2 Diabetes.
April 2018 in “D-Scholarship@Pitt (University of Pittsburgh)” This study found that keratin-75, discovered in enamel tissue, is secreted by ameloblasts using an unconventional pathway involving the ER-Golgi-Intermediate-Compartment and Golgi, differing from typical cytokeratin localization.
76 citations
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February 1993 in “Journal of Biological Chemistry” This research observed that sheep and rabbit KAP6 genes, expressed in hair follicle cells, have high sequence similarity and indicate conservation due to evolutionary selection pressures.
January 2010 in “BMC Genomics” This study found that KAP and KRTAP genes positively correlate with the cashmere growth cycle, and their regulation aligns with the growth phases of cashmere in secondary hair follicles.
February 2024 in “Frontiers in plant science” This study found that Plant Elicitor Peptides enhance root hair growth through a mechanism independent of their known receptors, with PROPEP2 playing a key role in this process by influencing gene expression related to root hair formation.
2 citations
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September 2023 in “Journal of the American Academy of Dermatology” CTP-543 effectively promotes hair regrowth in adults with moderate to severe alopecia areata.
September 2026 in “World Journal of Pharmacy and Pharmaceutical Sciences” In this study, a new hair serum featuring Catharanthus roseus extract was formulated and evaluated, showing a stable and appealing product with potential hair growth-promoting properties, positioning it as a promising herbal alternative to synthetic agents like minoxidil.
9 citations
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April 2010 in “Lung cancer” This study reported that a gemcitabine and pemetrexed regimen was moderately active in advanced NSCLC but did not offer an advantage over the paclitaxel and gemcitabine regimen and is not recommended for further evaluation.
4 citations
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August 2024 in “Journal of Cosmetic Dermatology” This study reports that injecting a non-cross-linked hyaluronic acid compound into keratosis pilaris-affected skin led to significant improvements in roughness, redness, and overall skin condition, while maintaining a favorable safety profile, making it a promising alternative treatment option.
1 citations
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December 2025 in “PLoS ONE” This study evaluated the real-world safety of Tepotinib for treating NSCLC with METex14 skipping mutations, confirming known adverse events and identifying new signals like deafness and taste disorder, especially highlighting early monitoring.
13 citations
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August 2018 in “Life sciences” This meta-analysis suggests that combining Kang-ai injection with platinum-based chemotherapy may improve tumor response, performance status, immune functions, and reduce adverse reactions in patients with advanced non-small cell lung cancer.
8 citations
,
November 2010 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that calcitriol protects keratinocytes from the cell detachment and apoptosis caused by captopril exposure.
153 citations
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January 2001 in “Science” In a neonatal rat model, this study found that topical CDK2 inhibitors reduced chemotherapy-induced hair loss in 33 to 50% of the animals, suggesting a potential strategy for preventing alopecia in cancer patients.
11 citations
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May 2013 in “Journal of Investigative Dermatology” KRTAP10 proteins help form the hair shaft's tough outer layer by interacting with specific hair keratins.
24 citations
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January 2019 in “Theranostics” This study found that loss of the Pten gene in Lgr5+ hair follicle stem cells promoted squamous cell carcinoma formation through the Akt/β-catenin signaling pathway.
30 citations
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February 2017 in “Histochemistry and Cell Biology” This study found that applying TPA to mice accelerated hair follicle regeneration by activating Akt and Wnt/ß-catenin signaling pathways, involving hair follicle stem cell proliferation.
1 citations
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June 2023 in “Animals” In this study, researchers found that overexpression of CRABP2 enhanced the proliferation of dermal papilla cells in Hu sheep through activation of the Wnt/β-catenin pathway, even when the pathway was inhibited.
53 citations
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June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This article reviews extensive genetic polymorphisms in the keratin-associated proteins of human hair, indicating complexity but reporting no new clinical results and calls for further research on their potential impact on hair structure.
35 citations
,
February 2012 in “The New England Journal of Medicine” Early diagnosis and treatment of TPP can prevent complications.
146 citations
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May 2002 in “The American journal of pathology” This study found that cathepsin L deficiency in mice led to significant abnormalities in hair follicle development and cycling, including disrupted hair shaft outgrowth and premature hair growth phase entry.
May 2025 in “Texas Digital Library (University of Texas)” In this study, researchers using Arabidopsis thaliana found that adenosine may inhibit root hair growth and stomatal opening, suggesting it plays a signaling role in plants similar to its function in animal cells, potentially revealing a new adenosine-like receptor pathway.
7 citations
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January 2019 in “Journal of Pharmacy And Bioallied Sciences” This study identified the major component of katuk leaf water extract as an alkaloid compound with a molecular mass of 406.3131 m/z, named (S, S)-5,5′-amino-4,4′-dihexyl-propyldihydropyrazol-3,3′-one.
100 citations
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March 2006 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that cystatin M/E strongly inhibits human cathepsin V and cathepsin L via distinct non-overlapping sites, suggesting an important role in human epidermal differentiation and hair follicle morphogenesis.
In this study, Paljeong-san pharmacopuncture reduced dihydrotestosterone levels and inhibited prostate tissue proliferation in a rat model of benign prostatic hyperplasia.
24 citations
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November 2009 in “Pharmaceutical Development and Technology” This study found that Transcutol P significantly enhanced the skin penetration of Finasteride in vitro, while cationic and anionic surfactants did not show such effects.
March 2013 in “Pigment Cell & Melanoma Research” This study revealed that different coat patterns in cats and cheetahs are related to variations in the aminopeptidase Q gene and endothelin-3 expression, which affects pigment production.
1 citations
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May 2019 in “International Journal of Applied Pharmaceutics” This study evaluated hair tonic and gel formulations containing Angiopteris evecta root water extract and found both fulfilled pharmaceutical preparation standards, with the 12.5% hair tonic and 10.0% gel concentrations most effective for hair growth without a significant difference in performance.
May 2020 in “Business Innovation & Entrepreneurship Journal” This study discusses the development of a turmeric-based herbal hair removal product named PASIKULA, highlighting its potential to increase the economic value of turmeric and acceptance by consumers.