Therapeutic Efficacy and Safety of Kang-Ai Injection Combined with Platinum-Based Doublet Chemotherapy in Advanced NSCLC: A Meta-Analysis

    August 2018 in “ Life sciences ”
    Qiang Lü, Cai-Lan Li
    TLDR Kang-ai injection with platinum-based chemotherapy improves tumor response and immune function while reducing side effects in advanced lung cancer.
    This meta-analysis evaluated the therapeutic efficacy and safety of Kang-ai injection (KA) combined with platinum-based doublet chemotherapy (PBDC) in treating advanced non-small cell lung cancer (NSCLC). Analyzing 30 randomized controlled trials with 1956 patients, the study found that KA combined with PBDC significantly improved tumor response, Karnofsky Performance Scale (KPS) scores, and immune functions (CD3+, CD4+, NK cells, and CD4+/CD8+ ratio) compared to PBDC alone. Additionally, the combination therapy reduced adverse reactions such as gastrointestinal issues, myelosuppression, and hair loss. Despite the small sample size and study limitations, the results suggested that KA combined with PBDC, particularly the NP regimen, could be a beneficial treatment strategy for advanced NSCLC. Further large-scale, rigorous randomized controlled trials were recommended to confirm these findings.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Hair Loss Results After 8 Months of Dutasteride

      in Progress Pictures  232 upvotes 2 weeks ago
      The user experienced increased hair density after 8 months of using dutasteride and 6 months of oral minoxidil. Some users joked about side effects, while others discussed the effectiveness of various treatments like finasteride and rosemary oil.

      community Hair Loss Due To Chlorine and Hard Metals In Water?

      in Research/Science  1 upvotes 1 month ago
      Hair loss possibly caused by chlorine and heavy metals in water was addressed by using a shower filter, ketoconazole shampoo, and PRP sessions, which stopped the hair loss but did not lead to regrowth. Other users suggested similar experiences and solutions, emphasizing the importance of a good water filter and patience for potential regrowth.

      community Hair Loss Treatments and Hair Transplant

      in Progress Pictures  4 upvotes 1 month ago
      The user is experiencing hair loss and is using oral finasteride, considering adding RU58841 and microneedling, and planning a hair transplant. They are seeking advice on whether to wait for treatment results or proceed with the transplant.

      community Hair loss steps, guide to beginners or anyone experiencing hair loss

      in Treatment  1 upvotes 1 month ago
      The conversation discusses a hair loss treatment regimen involving finasteride, dutasteride, spironolactone, bicalutamide, oral estradiol, microneedling, and minoxidil. The regimen aims to reduce androgenic alopecia by blocking DHT and androgens, with a caution about potential feminizing effects.

      community Hair loss 30F - thoughts on red light therapy vs min/fin?

      in Female  6 upvotes 1 month ago
      The conversation discusses hair loss treatments for a 30-year-old female, comparing red light therapy with minoxidil and finasteride. Concerns about hormonal impact and potential pregnancy are raised, with suggestions to consider spironolactone and microneedling, while emphasizing the importance of consulting a dermatologist.

    Similar Research

    5 / 1000+ results