A Prospective Observational Study on Drug Safety Monitoring and Pharmacoeconomics in Patients with Locally Advanced Unresectable NSCLC in a Tertiary Care Hospital

    March 2018 in “ International journal of basic and clinical pharmacology ”
    Jayakumar Sreenivasan, Seema P. Mohamedali
    Image of study
    TLDR Carboplatin-paclitaxel is preferred for advanced lung cancer due to its balance of affordability and patient well-being.
    The study observed 40 patients with locally advanced unresectable carcinoma lung over 2 months at a tertiary care hospital to monitor adverse drug reactions (ADRs) from chemotherapy and assess the economic burden of treatment. ADRs were graded using WHO guidelines, and patients' performance statuses were evaluated with Zubrod’s performance scale. The results showed that alopecia and peripheral neuropathy were significantly more common in patients treated with the carboplatin-paclitaxel combination than with other regimens (p < 0.005). Cost analysis indicated that while carboplatin-paclitaxel is more affordable than newer, more expensive agents, it is costlier than cisplatin-based chemotherapy. Despite this, the carboplatin-paclitaxel combination maintained a reasonably good performance status in patients. Consequently, the study concluded that carboplatin-paclitaxel is the preferred regimen for palliation in patients with advanced NSCLC, particularly in older patients.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Shedding again after 6 months of great results.

      in Minoxidil  15 upvotes 1 year ago
      A user experienced shedding after 7 months on Fin/Min spray despite good results and no change in treatment. Other users noted similar experiences and mentioned that shedding periods can be normal.

      community My experience with rosemary oil

      in Product  42 upvotes 3 years ago
      The user's experience with rosemary oil as a hair loss treatment and its effectiveness; they discuss other treatments such as finasteride, minoxidil, and RU58841; there is also discussion of combining oils like peppermint oil, zix, and dermapen.

      community Could you tell this is a hair system?

      in Technology  307 upvotes 3 years ago
      A user who was losing their hair and found an effective solution; they asked for opinions on it and discussed treatments such as Minoxidil, Finasteride, and RU58841, as well as SMP.

      community 11 months on fin only. Regrowth + thickness

      in Progress Pictures  572 upvotes 2 years ago
      A user reported hair regrowth and increased thickness after 11 months using finasteride 1mg, taken 3-4 times a week, with noticeable improvement starting around the third or fourth month. No side effects were mentioned, and the user is considering reducing the dosage to find the minimum needed to maintain results.

    Similar Research

    5 / 1000+ results