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GlossaryMyelosuppression

condition where bone marrow produces fewer blood cells

Myelosuppression is a medical condition where the bone marrow's ability to produce blood cells is decreased. This can lead to a reduction in red blood cells, white blood cells, and platelets, causing anemia, increased risk of infection, and bleeding problems. It is often a side effect of chemotherapy or radiation therapy used in cancer treatment.

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research Ayurveda-Based Botanicals as Therapeutic Adjuvants in Paclitaxel-Induced Myelosuppression

12 citations, February 2022 in “Frontiers in Pharmacology”

Asparagus racemosus and Withania somnifera can help reduce side effects of a cancer drug.

research Azathioprine-Induced Severe Myelosuppression Accompanied by Massive Hair Loss and Painful Oral Ulcer in an Autoimmune Hepatitis Patient with NUDT15 Minor Variant: A Case Report

3 citations, August 2021 in “Clinical Case Reports”

Genetic testing is crucial before giving azathioprine to avoid severe side effects.

research Case Report: NUDT15 Polymorphism and Severe Azathioprine-Induced Myelosuppression in a Young Chinese Female with Systemic Lupus Erythematosus: A Case Analysis and Literature Review

1 citations, May 2023 in “Frontiers in Pharmacology”

Genetic screening for NUDT15 polymorphisms is crucial for patients taking azathioprine, especially in Asians.

research Managing Azathioprine-Induced Myelosuppression and Alopecia Totalis: Lessons from a Systemic Lupus Erythematosus Patient

January 2024 in “Journal of Clinical Rheumatology and Immunology”

Monitor for early signs of myelosuppression, like hair loss, in patients on azathioprine to manage side effects.

research A Case of Azathioprine Induced Severe Myelosuppression and Alopecia Totalis in IgA Nephropathy

April 2017 in “Childhood Kidney Diseases”

Azathioprine can cause severe blood issues and hair loss, needing careful monitoring and possible discontinuation.

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