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GlossaryMyelosuppression

condition where bone marrow produces fewer blood cells

Myelosuppression is a medical condition where the bone marrow's ability to produce blood cells is decreased. This can lead to a reduction in red blood cells, white blood cells, and platelets, causing anemia, increased risk of infection, and bleeding problems. It is often a side effect of chemotherapy or radiation therapy used in cancer treatment.

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research Azathioprine

42 citations , January 1998 in “BioDrugs”

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

research Concomitant Alopecia Areata and Profound Bone Marrow Suppression: An Unusual Manifestation of Azathioprine Toxicity

July 2025 in “Clinical Dermatology Review”

Azathioprine can cause unexpected hair loss and severe bone marrow issues, so careful monitoring is needed.

research Azathioprine

March 2016 in “Reactions Weekly”

A woman experienced hair loss, nail changes, bone marrow suppression, and low blood protein after taking azathioprine.

research Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy

522 citations , January 2001 in “Cancer investigation”

Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.

Methotrexate Treatment Patterns in Advanced Therapy-Naïve Patients with Rheumatoid Arthritis: Clinical Characteristics and Outcomes of Patients in the Corrona Registry

research Methotrexate Treatment Patterns in Advanced Therapy-Naïve Patients with Rheumatoid Arthritis: Clinical Characteristics and Outcomes of Patients in the Corrona Registry

June 2019 in “Poster presentations”

Most patients with rheumatoid arthritis continued methotrexate treatment over two years, but those who stopped and restarted experienced more side effects and less improvement.

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