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In this study, IL-6 expression in transgenic mice thickened the stratum corneum without causing increased epidermal proliferation or inflammation, suggesting it may enhance skin protection rather than directly induce inflammation.

This study suggests that specific combinations of human type I and II hair keratins, particularly K35-K85 and K36-K81, have distinct in vitro assembly properties that are significant for macrofibril formation.

This study found that KRT6A expression increases after epidermal barrier disruption, worsening skin inflammation in disease conditions, and suggests that targeting KRT6A could offer a new treatment approach for inflammatory skin diseases linked to epidermal dysfunction.

This study shows that keratin 2e exhibits distinct temporal and regional expression patterns in fetal epidermis, suggesting different regulatory and functional roles from other epidermal keratins.

This study identified the expression sites of five KAP5 genes on human chromosome 11q13.5 in scalp skin sections but did not explore their detailed distribution within hair follicles.

This study successfully cloned the KAP6.1 gene from Xinjiang fine-wool sheep and found its genetic sequence has high homology with sheep and goat sequences, indicating close genetic relationships.

This research identified K31 as a new marker for distinguishing clear secretory cells in human eccrine sweat glands, aiding in differentiating between distinct cell types within these glands.

This study investigated the expression of KRTAP6 gene family in Gansu Alpine fine-wool sheep, finding significant expression during the anagen phase and a negative correlation between KRTAP6-1 and KRTAP6-5 expressions with wool fiber diameter and strength.

This review discusses cornea-specific keratin expression patterns in human and mouse development and reports no new experimental results; it highlights the need for investigating keratin mutations' role in pathology.

This study found that a highly resistant structure, located at the interface between the cuticle and cortex of human hair, acts as a penetration barrier, which the authors propose to name the "cuticle anchored resistant base" or CARB.

Keratin in mouse hair follicles is complex and plays specific roles.

KAP8.1 protein is crucial for hair structure and interacts with keratin 85.

This paper reviews the complex histology of skin layers and underscores its importance for accurate and reproducible diagnosis in cutaneous pathology, but reports no new research findings.

In this study, a new shading model for hair was developed that better matches real-life light scattering, thanks to detailed new measurements of hair fiber scattering not predicted by existing models.

This study found that high levels of human cytokeratin 16 expression in transgenic mice lead to skin lesions and altered keratinocyte structure, suggesting potential implications for human skin disorders and wound healing.

This study explored the epigenetic mechanisms of dermal fibroblast progenitor differentiation and found that the repressive chromatin profile from H3K27me3 prevents these progenitors from reforming skin in allograft assays, despite their multipotent potential.

This study found that keratin filament networks in SG1 cells of mice undergo dynamic changes during cornification, impacting the barrier function of the stratum corneum.

In this study, transfection experiments showed that mutations in the K85 gene affect filament formation with K35, which may impact hair formation related to ectodermal dysplasia.

In this study, researchers identified the ventral matrix as the primary source of nail plate formation, while the dorsal portion is generated by the apical matrix.

This review discusses the paradoxical effects of valproic acid on hair, noting that it can both cause alopecia and stimulate hair growth, but reports no new experimental findings.

This study confirms that the proposed universal model for hard α-keratin structure applies to all known forms across various mammalian species.

This study proposed a network model for the cross-linked structure of keratin-associated proteins in hair and wool fibers, suggesting notable differences between the two, potentially affecting hair fiber elasticity.

This study found that recombinant human hair keratin proteins K31 and K81 show greater potential for inducing skin cell differentiation compared to natural keratin coatings.

This study demonstrated that a specific 9-kbp fragment of the bovine keratin 6 gene effectively directs tissue-specific and inducible expression in transgenic mice, suggesting potential applications for targeted gene therapy in hyperproliferative skin conditions.

Keratin-associated proteins are crucial for hair strength and structure.

The study improved understanding of keratin fiber structure by showing consistent microfibril diameter but varying distances and electron density profiles.

This article discusses the human KRT72 wild-type allele's role in hair formation and reports no new research findings.

This study identified distinct gene expression programs in keratinocytes responsible for forming hard scales and soft interscale epidermis in chickens, revealing conserved differentiation genes similar to those in human skin.

This study reported that keratin films lacking keratin-associated proteins showed different appearance, structure, and color deposit properties compared to conventional keratin films, suggesting potential for evaluating hair damage.

This study introduced a new hair shading model that more accurately simulates light scattering on hair fibers, capturing effects not predicted by previous models.