Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study describes the expression patterns of type I inner root sheath keratin proteins K25–K28 in human hair follicles, highlighting their distinct distribution within different layers.

This study found that reduced cytokinin levels allow plants to adapt to low potassium conditions by enhancing root hair growth, reactive oxygen species accumulation, and expression of a key potassium transporter gene.

This study found that beard hair medulla cells express an unexpected range of keratins, showing variability and promiscuous behavior in keratin interactions distinct from other hair follicle cells.

This study found that cysteine supplementation significantly increases keratin expression in human keratinocytes, and counteracts the negative impact of iron deficiency on keratin production by enhancing iron availability for cellular processes.

This review summarizes the cell type distribution and functional significance of human keratins, emphasizing their roles in tumor diagnosis and potential clinical applications, and reports no new clinical findings.

This review discusses the role of keratins in epithelial cell stress protection and cancer, highlighting their potential as multifunctional regulators and diagnostic markers, without presenting new research findings.

Keratins are crucial for cell structure, growth, and disease risk.

This review discusses the genetic factors involved in hair follicle morphogenesis and cycling and reports no new clinical results; it emphasizes the role of genes in hereditary hair diseases.

This review discusses the role of keratins in maintaining epidermal structure and function and reports no new results; the authors emphasize the lack of rational therapies for skin disorders linked to keratin mutations.

This study found that prolactin is a key regulator of keratin expression in human hair follicles, enhancing specific keratin types and influencing epithelial stem cell-associated keratins.

This study found that the creation of hair follicle lumens in mice is driven by the outward migration of keratin 79-positive cells, suggesting a novel mechanism for generating hollow cores in hair follicles.

This chapter reviews keratins in skin epithelia, including their roles in cellular function and disease, and reports no new experimental results.

This study identified a mutation in the keratin 71 gene that causes curly hair in certain rats, advancing our understanding of hair formation.

This study found an association between a splice site variant in the KRT71 gene and curly hair in Selkirk Rex cats, identifying a significant locus on chromosome B4.

This study suggests that the keratins found in reptile and bird skin appendages evolved independently from mammalian hair keratins, highlighting convergent evolution in these species.

This study reports that structural abnormalities in the inner root sheath of hair follicles may cause the hair shaft to be loosely attached in patients with loose anagen hair syndrome.

This review discusses how neuroendocrine pathways influence keratin regulation in human skin and hair follicles and suggests these pathways as potential targets for new treatments of skin disorders, but reports no clinical results.

This study identified distinct gene expression patterns in wool follicle bulbs that may play important roles in wool follicle cycling and regeneration in sheep.

This paper reviews the genetic aspects of hair disorders and suggests that understanding these genes could advance treatment and diagnosis; it reports no new experimental findings.

This study found that melatonin at 0.2 g/L for 72 hours most effectively enhances cashmere growth in Liaoning cashmere goats by upregulating the lncRNA MTC, which activates NF-kB signaling.

In this study, researchers found that non-invasive analysis of skin surface lipid RNAs revealed alterations in gene expression patterns associated with atopic dermatitis, suggesting its potential for understanding skin disease pathophysiology.

This study suggests that β-catenin plays an important role in wool follicle development in transgenic sheep by enhancing the expression of keratin protein genes.

This study identified genes potentially involved in hair and cashmere growth in the Laiwu black goat, highlighting specific gene expression differences between hair-growing and hairless skin.

This study found that skin surface lipids contain measurable mRNAs, providing a non-invasive way to study skin diseases, with specific gene expression changes observed in atopic dermatitis patients.

In this study, DOP treatment improved hair regrowth in androgenetic alopecia by altering local steroid metabolism and follicular morphology.

This review examines the potential of K18 as a diagnostic and prognostic marker in epithelial-derived tumors, highlighting its specific expression in tumor tissues and interaction with proteins involved in tumor progression, without reporting new clinical findings.

This study describes the use of a genetically engineered mouse model, mTurquoise2-Col4a1, to fluorescently label collagen IV and observe basement membrane dynamics during skin development, revealing its stability and pliability during rapid growth phases.

This study found that many conditions in patients with COVID-19 were significantly increased compared to controls, with specific phenotypes identified across different demographic and diagnostic attributes.

This study identified a specific genetic variant in the CCHCR1 gene that may contribute to alopecia areata through impaired keratinization, suggesting an alternative mechanism beyond autoimmune causes.

Dermatologists give better information on pathology forms, hypersensitivity vasculitis is a common skin issue, misdiagnoses can occur, and various skin conditions are linked to loss of elastin or genetic factors.