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Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

GDNF helps grow hair and heal skin wounds by acting on hair stem cells.

The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.

Wnt ligands are crucial for hair growth and repair.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Further research is needed to improve hair regeneration using stem cells and nanomaterials.

MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Exposure to 50 Hz electromagnetic fields may help mice grow hair faster.

Researchers found a new way to create hair-growing structures in the lab that can grow hair when put into mice.

Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.

Hemp seed biomaterials may reduce hair loss and improve hair growth.

Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.

Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.

Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.

NF-κB is crucial for different stages and types of hair growth in mice.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.

The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.

Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.

Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.

Plasmalogens activate a channel in cells that may stimulate hair growth.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

High-dose radiation speeds up aging in skin stem cells.

The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.