48 citations
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June 2000 in “Japanese Journal of Cancer Research” This study found that dimethylarsinic acid significantly accelerates skin tumor development in hair follicle-targeted K6/ODC transgenic mice.
January 2018 in “대한본초학회지(본초분과학회지)” This study found that SHJ extract increased hair growth and melanogenesis in mice, suggesting potential use in cosmeceuticals for hair care.
April 2025 in “Drug Design Development and Therapy” This study observed that the herbal extract WJWE promoted hair growth and protected hair follicle cells in a DHT-induced murine model of androgenetic alopecia, potentially by engaging the SIRT1/JNK/p38 MAPK and Wnt5A/β-Catenin signaling pathways.
10 citations
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May 2019 in “BMC Complementary and Alternative Medicine” This study found that Bacillus/Trapa japonica fruit ferment filtrate extracts enhanced human hair follicle dermal papilla cell proliferation through the Akt/ERK/GSK-3β signaling pathway, suggesting potential benefits for alopecia treatment.
19 citations
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February 2001 in “Journal of paediatrics and child health” This report documents a 14-year-old Chinese boy with mitochondrial encephalopathy, lactic acidosis, stroke-like episodes, and a de novo A3243G mitochondrial DNA mutation, highlighting the condition's multisystem involvement without ragged red fibers in muscle biopsy.
1 citations
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July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” In this open-label trial, Tofacitinib was well tolerated and improved IFN and cytokine scores, as well as overall skin pathology, in individuals with Down syndrome and immune skin conditions.
5 citations
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April 2022 in “Cell Biology International” This study found that JAM-A modification in mouse wound models significantly promoted wound healing and fibroblast proliferation, potentially linked to increased levels of growth factors bFGF and EGF.
30 citations
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August 2005 in “British journal of dermatology/British journal of dermatology, Supplement” This study identified a novel CDH3 mutation associated with sparse hair and pigmentary macular changes in two siblings with hypotrichosis but no visual symptoms.
October 2023 in “Case reports in dermatological medicine” In this case report, a 45-year-old Jordanian woman was diagnosed with Clouston syndrome, an autosomal-dominant disorder characterized by alopecia and nail dystrophy due to a mutation in the GJB6 gene, though she lacked the typical palmoplantar keratoderma.
January 2025 in “Dermatology Reports” This case report describes a 61-year-old Italian man with a rare, localized variant of junctional epidermolysis bullosa linked to the R795X mutation in the COL17A1 gene, highlighting the importance of precise diagnosis for effective management of rare genetic disorders.
May 2018 in “Dermatologic Surgery” This overview highlights the Dermatologic Surgery journal's comprehensive coverage of dermatologic surgical procedures, but it reports no new research findings.
8 citations
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February 2014 in “Stem cells translational medicine” This study found that human mesenchymal stem cells overexpressing JAM-A improved hair follicle structure and hair formation in mice by reducing abnormalities such as curved and zigzagged follicles.
September 1998 in “Hair transplant forum international” This article shares personal observations from attending the Japanese Society for Hair Restoration meeting, with no new empirical results reported.
December 2025 in “ILDS-DEV” 1 citations
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January 1999 in “Dermatology”
September 2022 in “XXXIX Congresso Brasileiro de Reumatologia” In this case report, a 42-year-old woman with cutaneous dermatomyositis showed significant improvement, including reduction of erythema, pruritus, and scaling, after starting JAK inhibitor tofacitinib, especially when conventional systemic treatments failed and intravenous immune globulin wasn't viable.
15 citations
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November 2012 in “Archives of Ophthalmology” This description of dystrophy hypotrichosis associated with juvenile macular dystrophy provides an overview of this rare disorder characterized by short hair from birth and progressive loss of central vision but reports no new findings.
11 citations
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February 2022 in “JAAD case reports” This case report observed hair regrowth following the treatment of alopecia universalis and atopic dermatitis with tofacitinib, a JAK inhibitor.
10 citations
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August 2023 in “The EMBO Journal” This study explored the epigenetic mechanisms of dermal fibroblast progenitor differentiation and found that the repressive chromatin profile from H3K27me3 prevents these progenitors from reforming skin in allograft assays, despite their multipotent potential.
2 citations
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December 2024 in “eLife” This study observed that individuals with Down syndrome exhibit early immune dysregulation, including multi-organ autoimmunity and hypercytokinemia, and found that the JAK inhibitor tofacitinib showed a good safety profile and reduced skin pathology in a Phase II trial.
141 citations
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March 2011 in “Journal of Dermatology” This study in Japan found varying prevalence of skin disorders, with atopic dermatitis common in children and tinea pedis in the elderly, and observed gender differences in disease susceptibility.
September 1997 in “Hair transplant forum international” This article does not provide new research results but describes personal impressions from a meeting and acknowledges Prof. Wakamatsu's contributions.
February 2005 in “Journal of the American Academy of Dermatology”
July 2019 in “Journal of Aesthetic Nursing” This article discusses the JCCP's new Premises Standards for aesthetic practitioners, focusing on how these guidelines help ensure patient safety, and reports no new research findings.
16 citations
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June 2018 in “JAAD case reports” This article reviews the differences in inflammatory processes between alopecia universalis and atopic dermatitis, focusing on type 1 and type 2 immune responses, but it reports no new results.
16 citations
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April 2000 in “Contact dermatitis” In this report, a 19-year-old Japanese man experienced severe and prolonged urticarial reactions following treatment with diphenylcyclopropenone for alopecia universalis, emphasizing the need for caution with potent sensitizers.
This scoping review seeks to map existing research on appearance care and self-management for adolescent and young adult cancer survivors in Japan, aiming to highlight knowledge gaps and guide future studies and interventions to enhance supportive care for this population.
August 2022 in “Precision Clinical Medicine” This study found that the 3' UTR of JAM-A acts as a key competing endogenous RNA that supports dermal papilla cell function and hair follicle regeneration in alopecia areata.