A Case of Atopic Dermatitis with Alopecia Universalis in a Patient Treated with Abrocitinib

    February 2022 in “ JAAD case reports
    Jiahui Zhao, Lingling Liu
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    Studysummary This case report observed hair regrowth following the treatment of alopecia universalis and atopic dermatitis with tofacitinib, a JAK inhibitor.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    A 14-year-old girl with severe atopic dermatitis (AD) and alopecia universalis (AU) experienced significant hair regrowth and improvement in AD symptoms after 52 weeks of daily oral abrocitinib (200 mg), a Janus kinase (JAK) 1 inhibitor. Despite a mild relapse of AD, the patient remained satisfied with the treatment outcome, and no significant side effects were observed. This case suggests that abrocitinib can be an effective therapeutic option for patients with AD and refractory AU.
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