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A man with Klinefelter syndrome had a leg ulcer that didn't heal well, even with treatment.

A thorough history and examination are crucial for diagnosing skin diseases, which affect up to a third of people. This includes details about skin lesions, medication, general health, lifestyle, family, and contacts, as well as examining the rash, hair, nails, and mucous membranes. Changes in hair and nails can also indicate other medical and skin disorders.

Hair loss affects self-esteem; patients seek effective, low side-effect treatments.

Minoxidil helps with hair regrowth in women with androgenic alopecia.

Minoxidil solution increases hair growth; Shampoo B best for dandruff; infliximab helps pemphigus vulgaris.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Most patients with frontal fibrosing alopecia are postmenopausal women, and treatments like finasteride and dutasteride can improve or stabilize the condition.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.

Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

COVID-19 can cause different skin symptoms that may help with early diagnosis and show how severe the disease is.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Mostly postmenopausal Caucasian women get Frontal Fibrosing Alopecia, which often includes eyebrow loss and has limited treatment success.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Horizontally sectioned scalp biopsies are more reliable for diagnosing hair loss in women when three samples are taken instead of one.

Turmeric may have benefits for skin health, but more research is needed to confirm its effectiveness.

Coal tar shampoos, salicylic acid, and topical corticosteroids are effective for scalp psoriasis, with Vitamin D3 analogues also showing benefits; severe cases may require stronger medication with more risks.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Many people had severe allergic reactions to a common hair dye ingredient, causing them to seek medical care and miss work.