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Various medicinal plants like Polygonum multiflorum, Red ginseng extract, and Zizyphus jujuba can potentially treat hair loss, offering benefits like low cost and multiple ways of working. Other effective natural substances include Pygeum africanum, Seneroa, Urtica dioica, and more.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

Dutasteride effectively treats benign prostatic hyperplasia and may reduce prostate cancer risk.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

Removing PLCg1 from skin cells caused thicker oil glands and less hair in mice.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.

Minoxidil may help treat hair loss by reducing the activity of a specific enzyme linked to baldness.

Involucrin gene expression is controlled by specific proteins and signaling pathways.

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Inhibiting ornithine decarboxylase may help prevent certain skin cancers.

Targeting ornithine decarboxylase can help prevent skin cancer.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Guava leaf extract may help treat hair loss and protect cells by blocking certain genes and fighting damaging molecules.

Gastric bypass surgery improved a woman's hormonal disorder without the need for medication.

Hibiscus rosa sinensis shows promise for treating various health conditions and promoting hair growth.

Annurca apple extract improved hair growth in mice and could potentially prevent hair loss.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Finasteride dosages should be adjusted based on CYP3A5 genotype and liver function to avoid side effects.

There are effective treatments available for baldness.

Accurate diagnosis and personalized treatment are crucial for managing women's hair loss.

Using a gel called Diclofenac can potentially cause hair to grow back in bald spots in older men.