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This study found that Ishige sinicola extract increased hair growth and cell proliferation in cultured vibrissa follicles and mice, suggesting potential benefits for treating alopecia through β-catenin activation and 5α-reductase inhibition.

This study found that Ishige sinicola ethanol extract and its butanol fraction can protect against lipopolysaccharide-induced muscle atrophy in C2C12 myotubes through antioxidant and anti-inflammatory activities.

In this study, Ishige sinicola extract was observed to improve bone density and structure in an animal model of estrogen deficiency-induced osteoporosis, suggesting its potential as a therapeutic option for postmenopausal osteoporosis by inhibiting osteoclast formation without cytotoxic effects.

This review highlights the therapeutic potential of hair follicle stem cells in tissue repair and hair regeneration, discussing the molecular mechanisms and the impact of natural compounds on stem cell properties, which may support the development of novel hair loss treatments.

This study found that Ishige sinicola extract stimulated osteoblast differentiation and bone formation in MC3T3-E1 cells, suggesting potential use for osteoporosis prevention and treatment.

This review discusses the use of Dermal Papilla cells as in vitro models for studying hair growth modulators, emphasizing their role in aiding the development of new hair treatments, but reports no new clinical results.

This article reviews mechanisms by which herbal ingredients may stimulate or inhibit hair growth, and it reports no new clinical findings while suggesting potential for developing hair loss treatments.

This review discusses various plants and herbal formulations traditionally used for hair growth and notes their potential as safer alternatives to synthetic hair loss treatments, but reports no new clinical results.

This study found that Undariopsis peterseniana extract may promote hair growth by activating specific cellular pathways, suggesting potential for treating alopecia.

This review summarizes preclinical and clinical information on herbal products for hair loss treatment, highlighting their mechanisms, follicular penetration, and potential side effects, suggesting they may offer alternatives to synthetic drugs with fewer side effects.

This study found that pretreating mouse skin with microneedles significantly enhanced the hair growth inhibitory effect of eflornithine cream, likely by improving its skin permeation.

In this study, minoxidil and human platelet lysate affected gene expression related to hair growth signaling pathways in mouse hair follicle cells.

This article reviews treatment options for androgenetic alopecia, highlighting potential uses of plant materials, but reports no new clinical results.

In this study, extracts from three Polynesian plants—Bidens pilosa, Calophyllum inophyllum, and Fagraea berteroana—were found to increase dermal papilla cell proliferation and modulate hair growth-related gene expression, suggesting potential for stimulating hair growth.

In this study, fenugreek seed extract showed significant androgenic and spermatogenic effects in male rats, likely through inhibiting testosterone metabolism, without impacting cardiovascular health.

This review evaluates laboratory models used in androgenetic alopecia research but reports no new findings, emphasizing the potential of human-derived 3-D models for future studies.

This study suggests that while complementary and alternative treatments for hair loss are becoming more popular, their effectiveness and mechanisms remain largely unverified.

This review article discusses the potential benefits of phytochemicals in hair care, highlighting their ability to improve scalp health, reduce dandruff, and promote hair growth, while emphasizing their safety and minimal side effects compared to conventional therapies.

This study found that 10% Citrus aurantium peel oil significantly promoted hair growth in ICR mice by reducing the time needed for hair growth initiation and completion, and by increasing hair length, follicle diameter, and count, showing potential as a hair growth agent.

In this research, a thorough review of hair loss issues and treatments identified the effectiveness of minoxidil and finasteride for alopecia in the scalp's vertex region, but noted concerns about their potential long-term effects, leading to increased interest in herbal therapies.

This chapter provides an overview of phytochemicals with properties to combat alopecia and discusses the potential of flavonoids, found in several herbs, as a safer alternative to synthetic hair loss treatments due to their long-term skin compatibility.

In this study, researchers found that a mixture of Saccharina japonica and Undaria pinnatifida (L-U mixture) promoted hair growth in mice comparably to 3% minoxidil. The L-U mixture stimulated hair growth-promoting genes and suppressed hair loss-related genes, suggesting its potential for hair loss treatments.

This study reviews how oxidative stress affects hair follicle development and hair growth, discusses antioxidant-based treatments for hair loss, and evaluates natural antioxidant products that promote hair growth, emphasizing the need for further research due to existing limitations.

This study indicates that activating K+ channels in dermal papilla cells alone may not promote hair growth, despite some openers being effective on certain channels.

This review examines the anti-alopecia effects of plant-derived phytochemicals and their mechanisms for promoting hair growth, but it reports no new clinical findings.

This study found that hair tonics with 5% and 10% licorice extract promoted hair growth in rabbits similarly to 2% minoxidil and were generally safe, although they caused mild eye irritation at the 2.5% concentration.

This study found that limonin may promote hair growth by enhancing anagen signaling through autophagy activation in rat dermal papilla cells, suggesting its potential as a natural treatment for hair loss.

In this review, researchers highlight recent findings on the cosmeceutical applications of phlorotannins from brown seaweeds, emphasizing their promising bioactive properties since 2020.

This study found that components in the kernel of Prunus mira Koehne, such as vitamin E and β-sitosterol, may promote hair growth in mice, possibly involving the Wnt/β-catenin signaling pathway.

This review describes various in vitro and ex vivo hair follicle models used to study hair growth and regeneration and explores their potential for developing hair loss treatments, but it does not report new results.