December 2025 in “Bioengineering” This review explains that dysregulated sebum secretion and composition contribute to acne and impaired skin barriers while highlighting factors like diet and hormones affecting sebaceous activity, and identifies novel molecular targets and model systems for future therapeutic developments.
August 2025 in “Pharmaceutics” This study evaluated methods to administer betulin in in vivo experiments and found that olive oil, food-grade lard, and other carriers increase betulin absorption in Wistar rats, while monitoring blood levels may aid future clinical research.
August 2025 in “International Journal of Molecular Sciences” This study found that sulforaphane-rich broccoli sprout extract significantly accelerated hair regrowth in a mouse model of androgenetic alopecia, suggesting its potential as a safe and effective natural therapy.
27 citations
,
January 2012 in “Current Topics in Microbiology and Immunology” This study found similarities in the regeneration processes of MRL mouse ears and axolotl limbs, involving G2 cell cycle arrest and nerve-dependent mitosis, but the role of p21 in axolotl limb regeneration remains uncertain.
2 citations
,
September 2019 in “Romanian Journal of Pediatrics” This review discusses the unique features of fetal wound healing that may enable scarless repair and reports no new experimental findings.
September 2019 in “Romanian Journal of Pediatrics” This article discusses the unique regenerative healing process in fetal skin that can occur without scarring, highlighting potential therapeutic targets to reduce fibrosis in postnatal wound healing.
8 citations
,
January 2024 in “Current Research in Food Science” This study found that using composite alginate hydrogels containing Aloe vera, CMC, and tragacanth can improve the encapsulation efficiency and protect pumpkin seed protein hydrolysates from degradation during simulated gastrointestinal digestion, potentially increasing their applicability as functional food components.
7 citations
,
August 2020 in “Current topics in medicinal chemistry” This review discusses emerging cancer treatment methods focusing on cellular mechanisms unique to cancer cells and concludes no new clinical results.
2 citations
,
June 2023 in “Current Nutrition & Food Science” This literature review highlights the therapeutic potential of the biflavonoid hinokiflavone, suggesting its biological importance against various cancers, inflammation, viral infections like COVID-19, and other conditions.
July 2024 in “Current Pharmaceutical Design” This study reviews advancements in the use of biodegradable polymers for wound healing, highlighting various polymer formulations and the observed enhancement of processes like cell proliferation and wound healing in both in-vitro and in-vivo experiments.
180 citations
,
January 2003 in “American Journal of Clinical Dermatology” This article reviews the effects of menopause on skin aging and suggests that hormone replacement therapy may help reverse some of these changes.
2 citations
,
July 1998 in “Dermatologic Clinics” This review examines the differences in dermatology practices between Europe and North America, noting that European dermatologists often prioritize evaluating patients' psychosocial factors and utilize nondrug treatments, unlike their North American counterparts.
39 citations
,
April 2011 in “Recent Patents on Drug Delivery & Formulation” This review discusses various applications of nanoemulsions in drug delivery and reports no new clinical results; it highlights the patents that cover these applications.
6 citations
,
March 2019 in “Dermatologic surgery” This study found that storing hair follicle grafts in chilled ATPv-supplemented saline was most effective for preserving trichogenic gene expression, compared to other storage solutions and temperatures.
2 citations
,
October 2004 in “Organic Process Research & Development” This review discusses U.S. patents in organic process development published in July and August 2004 and reports no new experimental results.
May 2025 in “Journal of research in pharmaceutical science.” In this study, researchers developed and tested a herbal hair serum using hibiscus, flaxseed, and aloe vera, finding that the optimal formulation effectively reduces frizz, enhances hair smoothness and glossiness, and provides moisturizing benefits without harmful ingredients compared to conventional hair serums.
January 1993 in “Side effects of drugs annual” This chapter covers various dermatological drugs, cosmetics, and topical agents, focusing on the properties and uses of propolis, but does not present new clinical findings.
139 citations
,
February 2014 in “Journal of Advanced Research” This review explores the impact of vitamin D deficiency on the skin from a dermatological perspective, but reports no new clinical results.
4 citations
,
February 2011 in “Nature Reviews Endocrinology” Metformin and thiazolidinediones are similarly effective for PCOS, but metformin is often preferred due to fewer side effects.
47 citations
,
October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
28 citations
,
January 2004 in “British Journal of Pharmacology” This study found that minoxidil provides cardioprotective effects in guinea-pig heart cells through selective activation of mitochondrial ATP-sensitive potassium channels.
105 citations
,
May 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that activation of the TRPV3 ion channel inhibits human hair growth by affecting hair follicles and outer root sheath keratinocytes.
421 citations
,
January 2015 in “Chemical Society Reviews” This review discusses recent advances in surface modification and endothelialization of biomaterials for vascular grafts, highlighting promising methods like gene engineering and targeting ligand immobilization to improve clinical outcomes.
127 citations
,
June 2006 in “International Journal of Pharmaceutics” This research found that liquid-state liposomes and niosomes may enhance finasteride delivery to pilosebaceous units in hamsters more effectively than gel-state vesicles or hydroalcoholic solution.
89 citations
,
February 1993 in “Journal of Medicinal Chemistry” This research article focuses on nonsteroidal inhibitors of human type I steroid 5-alpha-reductase but reports no new results.
68 citations
,
March 2002 in “Journal of pharmaceutical sciences” This study found that nonionic liposomes were the most effective vehicle for delivering reporter genes into the skin of rat pups, compared to other liposome and nonliposome formulations.
48 citations
,
February 2025 in “Nano-Micro Letters” This review summarizes the application of microneedles in treating various skin diseases and highlights challenges like low drug loading, noting no new clinical results are reported.
30 citations
,
September 2004 in “Experimental Dermatology” This study found that minoxidil did not significantly increase hair shaft elongation in ex vivo human hair follicle culture, questioning the suitability of this method for studying its hair-growth-promoting effects.
19 citations
,
September 2020 in “Pharmaceutics” This study investigated a new formula called SV-loaded nanospanlastics for topical application to treat androgenic alopecia. It showed similar effectiveness to minoxidil lotion but with fewer adverse effects when used to enhance dermal delivery and efficacy of sodium valproate.
18 citations
,
January 2013 in “International Society of Hair Restoration Surgery” This article discusses the importance of clinical biopreservation for cells and tissues in hair transplantation and regenerative medicine, reporting no new empirical findings.