Scarless Wound Healing: A Literature Review

September 2019 in “ Romanian Journal of Pediatrics ”

Ancuta Muntean, Ionica Stoica, Dan Mircea Enescu

TLDR Fetal skin can heal without scarring, offering insights for new scar-reducing treatments.

The review discussed the potential of fetal skin to heal wounds without scarring, highlighting its regenerative capabilities. It emphasized the importance of understanding the cellular and molecular mechanisms behind this scarless healing phenotype, as it could lead to new therapeutic targets for reducing scarring in postnatal wounds. The review aimed to summarize the unique features of the fetal wound healing process that could facilitate scarless wound repair.

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research Scarless Wound Healing: Finding the Right Cells and Signals

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The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.

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Injecting alpha-melanocyte-stimulating hormone in mice improved skin healing and reduced scarring.

research Distinct Fibroblast Lineages Determine Dermal Architecture in Skin Development and Repair

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research Mammalian Fetal Organ Regeneration

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Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.