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High and low doses of prednisolone helped 62% of children with severe alopecia regrow hair with some weight gain and mild acne as side effects.

Certain genes and nutrients like vitamin D, zinc, and omega fatty acids affect COVID-19 severity and infection risk.

In 2001, the FDA approved 12 new drugs for children to treat allergies, asthma, ADHD, birth control, and other conditions.

Alopecia areata causes hair loss due to an immune attack on hair follicles, influenced by genetics and environment.

Chemotherapy and cytokine therapy can cause various skin reactions, including hair loss and hypersensitivity.

Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.

Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.

Lichen planus is a chronic autoimmune disease that is hard to treat and more common in women.

Certain immune molecules and stress affect hair loss, and while genes play a role, more research is needed to fully understand and treat it.

Lupus is a complex disease that requires personalized treatment because it varies greatly between individuals.

Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.

Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

OCT can detect hidden hair follicles in alopecia areata, indicating potential hair regrowth.

Transplant patients on immunosuppressive medications have a higher risk of skin cancer, and managing this involves balancing medication with cancer risk.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

Effective treatments for severe alopecia areata are still lacking.

European dermatologic treatments focus on lifestyle and psychosocial factors, use diverse methods like baths and climate therapy, and emphasize the importance of diet and supplements for skin health.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Memory regulatory T cells need IL-7, not IL-2, to stay in peripheral tissues.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Oral tofacitinib may effectively treat hair loss in children with alopecia areata.

This therapy effectively treats resistant alopecia areata with minimal side effects.

Tofacitinib works better and is more tolerable for severe alopecia than conventional treatments and DPCP immunotherapy.

The article concludes that different types of hair loss require specific treatments and psychological support is important.

Terbinafine can cause hair loss.

Alopecia areata treatment should be personalized, using topical or systemic therapies based on severity, with promising options like JAK inhibitors needing more research.