Subsurface Detection of Hair Follicles in Alopecia Areata Using Optical Coherence Tomography

    January 2022 in “ Skin research and technology ”
    Ai Ping Yow, Wellington Zhengdao Lee, Damon Wing Kee Wong, Hong Liang Tey
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    TLDR OCT can detect hidden hair follicles in alopecia areata, indicating potential hair regrowth.
    This study investigates the use of optical coherence tomography (OCT) to detect subsurface hair follicles in patients with alopecia areata (AA). Conducted on 20 patients, the study found that OCT can visualize hair follicles at the dermoepidermal junction (DEJ), which are not visible on the scalp surface. The presence of these subsurface follicles likely indicates regrowing hair. OCT could potentially be used in clinical settings to monitor treatment responses and reduce the need for repeated steroid injections, thereby minimizing side effects. Further studies are needed to correlate OCT findings with clinical improvements in AA.
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