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    GlossaryDermal-Epidermal Junction (DEJ)

    interface where the epidermis connects to the dermis

    The Dermal-Epidermal Junction (DEJ) is a critical area of skin where the outer layer (epidermis) connects to the underlying layer (dermis). This junction plays a vital role in maintaining skin integrity, facilitating nutrient exchange, and supporting cellular communication. It is essential for wound healing and overall skin health, and its degradation can lead to various skin disorders.

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      community Both success and failure. 10 month minoxidil and 8 month finasteride

      in Treatment  15 upvotes 2 years ago
      The user has been using minoxidil at night and finasteride daily for several months, experiencing initial hair growth but later regression and thinning. They're considering switching to dutasteride and seeking advice on the cause of their hair loss and potential treatments.

      community Progreso de 3 meses usando minoxidil topico

      in Progress Pictures  2 upvotes 1 month ago
      The user started using topical minoxidil 5% and ketoconazole shampoo for hair loss, noticing minimal progress after three months, with fine hairs appearing. They experienced a setback when reducing the application to once a day but resumed twice daily applications.

      community Just Minoxidil 5% twice a day for 5 months

      in Progress Pictures  584 upvotes 2 months ago
      Significant hair regrowth was achieved using 5% Minoxidil twice daily and weekly microneedling with a 0.8 mm dermaroller over five months. Finasteride was not used due to concerns about side effects and availability in France.

      community When could we expect pp405 to hit the market?

      in Research/Science  30 upvotes 5 months ago
      PP405 is expected to finish Phase 2 trials in late 2025, with potential market availability around 2028-2029 if all goes well. Current treatments like finasteride and minoxidil are still popular, while new options like KX-826 and Breezula are anticipated soon.