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Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.

Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Abdominal skin heals faster than dorsal skin because it has more stem cells.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.

Vitamin D and calcium are important for skin stem cell function and wound healing.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.

KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.

Wnt signaling is crucial for skin development and hair growth.

Epidermal stem cells don't use gap junctions to communicate.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Artificial dermal template treatment can stimulate complete skin and hair follicle regrowth.

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

Collagen XVII is important for skin aging and wound healing.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Notch signalling helps skin cells differentiate and prevents tumors.

The conclusion is that FFA and LPP have similar scalp biopsy features, making them hard to distinguish histologically, and FFA may be a specific kind of scarring hair loss.

The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.

Skin can produce blood cells, often due to disease, which might lead to new treatments for skin and blood conditions.

Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.

Wnt signaling is crucial for skin wound healing and reducing scars.

Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.

Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.

Researchers successfully transplanted hair follicles in mice, which survived well and helped in wound healing.

Vitamin D and calcium are important for quick and effective skin wound healing.