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Cutaneous gene therapy could become a viable treatment for skin and hair disorders with improved vector development and gene expression control.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Lower GPX4 mRNA levels are linked to higher disease activity and symptoms in lupus patients.

Topical minoxidil showed promise for early male pattern baldness.

The skin microbiome helps heal wounds and can be targeted to improve healing.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

The study mapped yak skin cells to understand hair growth better.

Asparagus racemosus and Withania somnifera can help reduce side effects of a cancer drug.

Licorice has many health benefits but more research is needed to fully understand them.

Various treatments exist for alopecia areata, but none are completely satisfactory; choice depends on age, disease extent, and preference.

Genetics, stress, and health issues can cause early hair greying, which affects self-esteem, and there's no cure, only hair dye.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

scINSIGHT accurately identifies cell clusters and gene patterns in complex data.

A woman's eyelashes grew thicker and longer after taking topiramate, but returned to normal when she stopped the medication.

TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Licorice helps with acne, eczema, dandruff, hair growth, and skin health but may raise blood pressure.

A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.

Targeting TGFβ can improve skin immunity in older people.

Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

A woman with a rare scalp lymphoma had unusual hair loss after treatment.

The document concludes that changes in eyelashes and eyelid skin can indicate various local and systemic diseases.

Loss of a specific protein in skin cells causes symptoms similar to psoriasis.

Some immunosuppressed patients can get unusual skin infections from Malassezia, which can be treated with antifungal medication.

Scalp cooling is the only FDA-approved method to prevent hair loss from chemotherapy, but other treatments like minoxidil and PRP are being tested.

Shrinking of oil glands in the skin is a key sign of hair loss linked to TNF inhibitor drugs and may improve if the treatment is stopped.

The document says to treat cat fungal infections with medicine and clean the environment, noting that cats without symptoms can still spread it to humans.