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While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Women with PCOS are more likely to have sleep apnea, mainly if they are obese.

Prolactin may be important for skin growth and immune function.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

The conclusion is that a thorough approach is needed to diagnose and manage hyperandrogenism in teenage girls, recognizing its major psychological and health effects.

New guidelines stress early diagnosis and lifestyle changes to manage metabolic syndrome and prevent complications.

KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.

Men with male pattern baldness have a higher chance of heart disease, especially if they're younger or have severe baldness; no link was found with another type of baldness called alopecia areata.

Finasteride lowers good cholesterol, raises bad fats, and may increase heart disease risk.

Ageratum Conyzoides, when taken orally, can effectively reduce hair loss and improve hair growth.

Convolvulus arvensis ethanolic extract can potentially promote hair growth and reduce hair loss.

Many men with male pattern baldness have abnormal blood fat levels, which may raise their risk of heart disease.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

DHT may increase the risk of heart disease and death in elderly men.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Doctors need to be better prepared to assess and treat obesity in patients.

Hair loss links to higher death risk from diabetes and heart disease; not a direct cause, but a marker for risk factors.

Hormonal therapies are safe and effective for treating adult women's acne.