TLDR Finasteride lowers good cholesterol, raises bad fats, and may increase heart disease risk.
The study investigated the effect of finasteride on the lipid profile of 25 individuals with androgenetic alopecia. The results showed a significant decrease in HDL plasma level after 6 months of therapy and a significant increase in triglyceride plasma level after 3 months of therapy. No significant changes were observed in LDL and total cholesterol levels. The study suggests that the use of finasteride may increase the risk of atherosclerosis, and high-risk patients should be identified to avoid the use of 1 mg finasteride tablets. Lifestyle modifications and avoiding high-fat food may help counter the adverse effects of the drug. Further studies are needed to corroborate the findings.
24 citations,
January 2010 in “Endocrine Regulations” Taking 1mg of finasteride daily can mildly improve metabolic health and glucose regulation in men with male pattern baldness.
38 citations,
February 2009 in “Journal of The European Academy of Dermatology and Venereology” Severe vertex pattern hair loss may indicate a higher risk for artery plaque buildup.
72 citations,
April 2008 in “The Journal of urology/The journal of urology” Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.
14 citations,
March 2016 in “Journal of Dermatology” Hair loss links to high blood pressure, high fat levels, and metabolic issues, suggesting early heart disease screening.
January 2024 in “Journal of lipid research” Finasteride may lower cholesterol and slow heart disease progression.
November 2023 in “Australasian journal of dermatology” Dermatologists are essential in helping transgender and gender diverse patients with skin and hair issues related to gender affirmation and hormone therapy.
20 citations,
June 2017 in “Hormone Molecular Biology and Clinical Investigation” Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.
166 citations,
October 2018 in “Endocrine Reviews” Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.
