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Understanding Polycystic Ovary Syndrome (PCOS) and its causes can lead to effective treatments.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Late diagnosis of congenital adrenal hyperplasia can greatly affect physical development, gender identity, and sexual health.

Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

The journal covered various dermatology topics, including treatments, disease management, and research findings.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

Methotrexate treatment for rheumatoid arthritis has a serious infection rate of about two per 100 patient-years.

The book explains causes and treatments for common hair loss, its psychological effects, related health risks, and emphasizes early screening and lifestyle changes.

Certain drugs and supplements may contribute to hair loss in the frontal hairline in older women.

Women with Polycystic Ovary Syndrome have a higher chance of getting depressed.

Skin problems like excessive hair growth, acne, and dark skin patches can be signs of Polycystic Ovarian Disease, which may also be linked to family history and a risk for diabetes.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.

DN106212, an extract from a plant, is better at promoting hair growth than other tested substances by affecting hair growth factors and follicle development.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.

Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.

There is no significant link between male pattern baldness and insulin resistance.

The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.

Metformin improved insulin resistance and BMI in overweight Taiwanese women with PCOS, and a 2-hour insulin test may be a good screening tool.

Treating epilepsy is complex, requiring careful drug choice and patient adherence to manage seizures and side effects.

A 9-year-old girl developed type 1 diabetes and alopecia after being treated for a rare kidney disease.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

The YH complex, made from Astragalus membranaceus and Cinnamomum cassia, may help treat hair loss by promoting hair growth and follicle development.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.