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The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

A new carrier improves skin delivery of tofacitinib for treating inflammatory skin diseases.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

JAK inhibitors show promise for treating skin conditions like eczema, hair loss, and psoriasis.

Testosterone's effects on COVID-19 are unclear and need more research.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

Ifidancitinib, a JAK inhibitor, effectively regrows hair in mice with alopecia by tiring out harmful T cells.

Hemp is a promising ingredient for skin products due to its healing and soothing properties.

TLR4 is important in aging-related diseases and could be a new treatment target.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

CBD may improve skin and hair health, but its effective use and safety need more research.

New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.

Human foreskin does not show aging or reduced cell growth after radiation, and H2A.J is not a good marker for radiation-induced aging.

The stiffness of a wound affects hair growth during healing, with less stiff areas growing more hair.

The health of the gut may be important in developing new ways to prevent, diagnose, and treat alopecia areata.

A patient with alopecia had hair regrowth with tofacitinib but developed a skin reaction, choosing to continue the treatment despite the side effect.

Upadacitinib significantly improved a man's severe scalp condition when other treatments failed.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

The supplement highlighted advancements and challenges in plastic and reconstructive surgery, including the impact of smoking, chemotherapy, and new treatments like Tafluprost for hair loss.

Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Wound healing insights can improve regenerative medicine.

DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.

Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.