26 citations
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August 2018 in “Journal of Investigative Dermatology” This study found that TRPV3 activation in human sebocytes inhibits lipid synthesis and triggers proinflammatory cytokine expression, suggesting a role in the pathogenesis of dry skin-associated inflammatory dermatoses.
19 citations
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December 2021 in “Stem Cell Research & Therapy” This study found that Muse cells, when injected subcutaneously, alleviated symptoms of atopic dermatitis in mice, suggesting potential for treating inflammatory skin conditions.
In this case report, an African American male with signs of acne keloidalis nuchae highlights the condition's chronic nature and need for early intervention to minimize permanent scarring and its psychosocial impact.
June 2023 in “Benha Journal of Applied Sciences” This review concluded that interleukin-17 is involved in the development of female-pattern baldness, suggesting a potential inflammatory role in the condition’s underlying causes.
30 citations
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August 1993 in “PubMed” This study found that IL-1 alpha inhibits the growth of cultured human hair follicles and hair fibers, suggesting a potential role in inflammatory hair loss conditions like alopecia areata.
July 2025 in “Zagazig University Medical Journal” This review reported that exosomes have significant potential in dermatology for use as diagnostic markers and therapeutic tools, with implications for treating conditions like inflammatory skin diseases, skin aging, wound healing, and hair restoration.
April 2021 in “Journal of Investigative Dermatology” This study suggests that rather than inhibiting IL-15, selectively stimulating IL-15Ra-mediated signaling could be beneficial for managing alopecia areata and possibly other inflammatory hair loss conditions, as IL-15 promoted hair growth and maintained immune privilege in human hair follicles.
This study found that human hair follicle cells suppress immune activity, with somatostatin playing a significant role, suggesting potential applications for treating inflammatory hair loss conditions.
178 citations
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June 1994 in “Journal of Investigative Dermatology” This study found that a non-scarring alopecia in C3H/HeJ mice resembles human alopecia areata and may serve as a valuable model for studying specific subtypes of the human condition.
70 citations
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June 2023 in “International Journal of Molecular Sciences” In this review, researchers explored how air pollutants increase oxidative stress and inflammation in human skin, affect vitamin D synthesis, and interact with the skin microbiota, also discussing AhR/Nrf2 as a potential target for treating pollution-related skin conditions.
61 citations
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January 2018 in “Cosmetics” This review highlights the potential of coffee silverskin's bioactive compounds in combating skin aging and related conditions, suggesting it as a promising natural ingredient for cosmetics due to its antioxidant, anti-inflammatory, and anti-aging properties.
17 citations
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January 2011 in “Skin Research and Technology” Hair from people with seborrheic dermatitis is thicker scaled, more damaged, and thinner than healthy hair, and atomic force microscopy can help monitor the condition.
9 citations
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May 2005 in “Expert Review of Clinical Immunology” This article examines anticytokine therapies for autoimmune diseases, highlighting the potential of anti-interferon-γ as a universal treatment for certain conditions and noting varying effectiveness of tumor necrosis factor-α inhibitors.
8 citations
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April 2017 in “American Journal of Dermatopathology” In this study, nail matrix pathology in a patient with Cronkhite–Canada Syndrome revealed matrix hypergranulosis, suggesting that an inflammatory process may play a key role in the condition's pathogenesis.
7 citations
,
March 2016 in “Journal of Cosmetic and Laser Therapy” This review suggests that paradoxical hair growth after light-based treatments is unlikely due to the devices themselves; instead, it may be linked to other factors such as inflammation in individuals with certain conditions.
6 citations
,
August 2011 in “Anais Brasileiros de Dermatologia” This case report describes a 32-year-old man with therapy-resistant acneiform eruptions later diagnosed as vellus hair cysts, emphasizing the condition as a potential diagnostic consideration in similar cases.
6 citations
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March 2020 in “Jornal de Pediatria” This study found that inflammatory dermatoses, especially atopic dermatitis, were the most common pediatric skin conditions at a Brazilian reference center, highlighting different patterns compared to adult skin disorders.
6 citations
,
July 2011 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This case report describes a successful eyebrow reconstruction using hair follicle micrografts in a patient with dormant keratosis pilaris atrophicans, demonstrating potential for this technique in similar conditions.
3 citations
,
August 2020 in “PubMed” This review discusses the potential efficacy and applications of platelet-rich plasma in dermatology, highlighting its use in various skin conditions but reporting no new clinical results; the authors call for standardization of preparation and treatment methods.
3 citations
,
January 2016 in “Annals of Dermatology” This article discusses the multifactorial nature of acne, including its association with follicular hyperkeratosis, sebaceous lipids, Propionibacterium acnes, and perifollicular inflammation, but reports no new clinical findings.
2 citations
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May 2022 in “Acta dermato-venereologica” In this study, patients with frontal fibrosing alopecia showed more actinic damage than control subjects, suggesting sunscreen use by these patients may be a consequence rather than a cause of the condition.
2 citations
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January 2018 in “Dermatology Online Journal” This report describes a case of a 60-year-old woman experiencing inflammatory skin reactions after consuming ginseng and reviews the characteristics of its use in healthcare, although detailed descriptions of such effects are limited.
1 citations
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April 2025 in “Frontiers in Medicine” This editorial synthesizes research on UV-induced skin damage, highlighting potential therapeutic strategies by mapping cellular changes, identifying molecular mechanisms, demonstrating melanocyte protection, and proving combination therapy effectiveness in conditions like vitiligo.
1 citations
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February 2022 in “Experimental Dermatology” This study found that the secretory profiles of adipose-derived stem cells vary between balding and non-balding scalp areas in androgenetic alopecia patients, suggesting involvement of angiogenic and inflammatory processes in the condition's development.
1 citations
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April 2017 in “Journal of Investigative Dermatology” In this study, D-OCT imaging revealed distinct structural and vascular changes in patients with frontal fibrosing alopecia, highlighting the technique's potential for diagnosing and monitoring the condition's activity.
1 citations
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January 2010 in “Springer eBooks” This review discusses the role of androgen metabolism and perifollicular inflammation in the progression of androgenetic alopecia and reports no new clinical results.
1 citations
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January 2023 in “Elsevier eBooks” This review discusses the role of phospholipases in skin and hair health, suggesting that understanding their molecular control could inform new treatments for related conditions, but it presents no new clinical results.
May 2026 in “The FASEB Journal” In this integrative study, the researchers examined microRNA-mRNA networks related to androgenetic alopecia and found that miR-146b-5p may promote hair growth and improve inflammation, highlighting a potential therapeutic target for the condition.
In this case report, an 11-year-old girl with dissecting cellulitis of the scalp showed an excellent response to oral isotretinoin after other treatments failed, highlighting the treatment challenges and need for awareness in managing this rare condition.
December 2025 in “International Journal of Morphology” This animal study found that Prunus armeniaca L. seed oil improved inflammatory markers, oxidative stress levels, and skin structure in DNFB-induced seborrheic dermatitis in rats, suggesting its potential role in managing this condition.