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This study found that using 3D cultures and fetal tissue extracts significantly improved the outcomes of stem cell treatments for regenerative medicine, including hair follicle formation and chronic wound healing.

In this study, low-intensity ultrasound was investigated as a noninvasive method for promoting hair regrowth in androgenetic alopecia using C57BL/6 male mice, revealing that specific frequencies and intensities can safely enhance hair regrowth compared to controls by optimizing mechanical effects without causing unsafe cavitation.

This review highlights the complex interplay between intrinsic and extrinsic factors influencing skin aging, emphasizing the need for advanced human-specific models to study aging mechanisms and develop new therapies.

This study found that in murine dermis, fibroblast state switching between proliferation and ECM deposition plays a crucial role in tissue architecture and wound healing.

This study found that human scalp hair follicles transplanted onto chemotherapy-treated immunodeficient mice closely mimic chemotherapy-induced hair loss seen in cancer patients, providing a valuable model for research.

This study predicted that 6-hydroxy genistein, coreximine, and scoulerine from Dadap leaves may act as anti-alopecia agents by interacting with JAK2, but further in-vivo testing is needed.

This review discusses human epidermal neural crest stem cells (hEPI-NCSC) as candidates for cell-based therapies and drug discovery but reports no new experimental results.

Hard α-keratin in hair has a unique, nonordered structure, different from other fibers.

This review highlights the diverse roles of melanocytes in pigmentation, immunity, and hearing among other functions, their involvement in disorders, and their emerging potential in regenerative medicine, including applications in disease modeling and therapy development using advanced technologies.

This study found that finasteride delivered through a nano-transferosomal gel showed improved penetration through skin layers compared to a conventional gel, suggesting a potential alternative for oral administration.

This review discusses the various components essential for successful tissue engineering, such as cell sources, modification methods, and supportive matrices, and highlights the need for functional synergy without reporting new experimental results.

This review discusses the development and potential applications of organoids for human disease modeling and regenerative medicine but reports no new experimental results.

This review examined the role of organoid technology in modeling genetic diseases, highlighting its promise for understanding disease pathology and developing tailored treatments by integrating genetic insights with advancements in regenerative medicine and biological engineering.

This review discusses the development and application of cell-derived matrices in regenerative medicine and disease modeling, presenting various fabrication techniques and future perspectives, but reports no new results.

This review summarizes recent advances in organoid technology for generating tissue models from the three germ layers and reports no new experimental results.

This study explored how high glucose concentrations impact mesenchymal stromal cell survival in diabetic environments, highlighting mitochondrial factors as potential targets for enhancing cell viability.

This study established a new in vitro culture system that supports the growth and dynamic self-organization of hair follicle stem cells and their progeny, promoting a stable population equilibrium.

This study used machine learning to identify molecular predictors of drug response in alopecia areata, suggesting a tool for predicting treatment efficacy based on gene signatures.

This study reported that a subcutaneous injection formulation using PLGA microspheres to release finasteride stably achieved sustained monthly drug delivery without burst release in beagle dogs, with a dose of 16.8 mg identified as optimal for potential first-in-human trials.

This study examined the pharmacokinetics of finasteride in pigs and found that ketoconazole coadministration affected its distribution across various plasma compartments, bile, and urine.

This study found that hydro-alcoholic Eclipta alba extract may have anticancer and multidrug resistance-reversal effects in animal models, suggesting potential as an adjunctive agent in tumor chemotherapy.

In this study, the authors found that applying hypobaric pressure to the skin significantly increases the transdermal permeation of large molecules by enhancing diffusion, despite the associated skin stretching and hair follicle enlargement not fully explaining this effect.

In this study, researchers developed a mathematical model to explore how immune system dynamics affect hair follicle behavior in alopecia areata, identifying key parameters influencing disease progression and suggesting potential treatment strategies targeting immune dysregulation.

In this study, researchers examined a patient with ZMYM2::FGFR1 fusion-positive leukemia, finding that Pemigatinib showed efficacy, while Ponatinib resistance was linked to a specific FGFR1 mutation. Other FGFR inhibitors demonstrated high effectiveness in ex vivo assays.

This study developed a mathematical model to explore the interactions between hair cycle dynamics and immune system activity in alopecia areata, providing insights into disease progression and potential targets for treatment by simulating immune response effects on hair follicles.

This study found that Wnt signalling activates hair follicle fate in hair follicle stem cells by relieving TCF3/4–TLE-mediated repression, with β-catenin being crucial for this process.

This study suggests that passage number significantly affects in silico scratch assay results, highlighting the importance of reporting passage number for reproducibility in cell culture experiments.

This paper reviews the role of pharmacokinetic/pharmacodynamic modeling in drug development, emphasizing its application for drug dosing guidance, safety resolution, and therapeutic monitoring improvement, without presenting new clinical results.

This review outlines the transition from simple hair follicle organoids to immune-competent microphysiological systems, addressing limitations in replicating native hair follicle immune features and discussing their applications in disease modeling and regenerative medicine.

This study models the pathways of nandrolone and its metabolites in the body and suggests methods to counteract finasteride's role in enabling PED users to cheat drug tests.