research Simvastatin Decreases Alopecia Areata-Associated Inflammation Through Effects on Isoprenoid Metabolites
Simvastatin reduces inflammation and promotes hair regrowth in alopecia areata.
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research Atherogenesis: Estrogen Induction of Polysialylated NCAM Blocks Monocyte Capture by Vascular Endothelial Cells
Estrogen helps prevent artery plaque by stopping monocyte capture in blood vessels.
research Perifollicular Vascularization: Cocultures and Tricultures Approaches to Study the Cross-Talk Between Microvascular Endothelial Cells, Follicle Papilla Cells, and Keratinocytes
Hair papilla cells are crucial for blood vessel development in hair follicles, affecting hair growth and loss.
research Slowly Does It
Special astrocytes improved learning and memory in rats after a stroke.
research Making Magnesium Magnificent
Special astroglia cells improved stroke recovery in rats, a hair growth drug reduced cancer spread, and tiny magnesium structures were more easily shaped.
research Effect of Oil, Water, and Surfactant Mixture on the Physicochemical Properties and Transdermal Delivery of Finasteride-Loaded Microemulsions: Evaluation and Prediction Using Response Surface Methodology
A 3:1 surfactant mixture in microemulsions can effectively deliver finasteride through the skin.
research FGF Signaling Is Required for Initiation of Feather Placode Development
FGF signaling is crucial for starting feather development in chicken embryos.
research Hair Follicles as a Target Structure for Nanoparticles
Nanoparticles around 600-700 nm can effectively enter and stay in hair follicles for days, which may help in delivering drugs to specific cells.
research Androgens and Ovarian Function: Translation from Basic Discovery Research to Clinical Impact
Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
research The CD44+ALDH+ Population of Human Keratinocytes Is Enriched for Epidermal Stem Cells with Long-Term Repopulating Ability
Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
research Stem Cell Niches
Stem cell niches regulate the number and function of stem cells in the body.
research Management of Colorectal Cancer Using Nanocarrier-Based Drug Delivery for Herbal Bioactives: Current and Emerging Approaches
Nanocarriers can improve the effectiveness of herbal medicines in treating colorectal cancer.
research Novel Treatment of Alopecia Areata With Shooting-Type Candlelit-Dissolving Microneedle
New treatment for hair loss using special microneedles shows promise in reducing inflammation and promoting hair growth.
research LncRNA RP11-818024.3 Promotes Hair-Follicle Recovery Via FGF2-PI3K/Akt Signal Pathway
LncRNA RP11-818024.3 helps hair growth and recovery in hair loss by boosting cell survival and reducing cell death.
research Opsins and Cryptochrome Photoreceptors Mediate Blue Light Stimulatory Effect on Hair Growth
Blue light helps hair growth by affecting specific proteins in hair follicle cells.
research Induced Pluripotent Stem Cell Derived Keratinocyte Differentiation from Reprogrammed Blood Cells
Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.
research Abstract 152
TLR3 activation helps improve skin and hair follicle healing in mice.
research Vestibular Hair Cell Regeneration and Restoration of Balance Function Induced by Math1 Gene Transfer
Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.
research Hair Growth Promoting Effect of White Wax and Policosanol from White Wax on the Mouse Model of Testosterone-Induced Hair Loss
White wax and policosanol from white wax effectively reduced hair loss and promoted hair growth in mice better than a known hair growth drug.
research Formulation of Chloroaluminum Phthalocyanine Incorporated into PS-b-PAA Diblock Copolymer Nanomicelles
The PS-b-PAA copolymer nanomicelles are effective for delivering a cancer treatment drug in photodynamic therapy.
research Vitamin D Receptor Ablation Alters Skin Architecture and Homeostasis of Dendritic Epidermal T Cells
Lack of Vitamin D receptor changes skin structure and increases certain immune cells in the skin.
research MoS2 Nanoclusters-Based Biomaterials for Disease-Impaired Wound Therapy
The SA-MS hydrogel is a promising material for improving wound healing and skin regeneration in diseases like diabetes and skin cancer.
research HaCaT-Conditioned Medium Supplemented with Small Molecule Inhibitors SB431542 and CHIR99021 and Growth Factor PDGF-AA Prevents the Dedifferentiation of Dermal Papilla Cells In Vitro
A mix of specific inhibitors and a growth factor helps keep hair growth cells from losing their properties in the lab.
research Nanostructured Lipid Carriers Promote Percutaneous Absorption and Hair Follicle Targeting of Tofacitinib for Treating Alopecia Areata
Nanostructured lipid carriers effectively deliver tofacitinib to hair follicles, reversing hair loss in alopecia areata.
research Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
research Radiofrequency Current at 448 kHz for Female Pattern Hair Loss: Cellular Bases for Redensification Improvement
Using 448-kHz Capacitive-Resistive Electrothermal Therapy can help increase hair density and prevent hair loss in women.
research Androgenic Effects on Ventricular Repolarization
ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.
research Formulation and Evaluation of Finasteride Sustained-Release Matrix Tablets Using Different Rate Controlling Polymers
Finasteride, a drug used for anti-hyperplasia, can be effectively delivered in the form of matrix tablets.
research Treatment Options for Polycystic Ovary Syndrome
Different treatments for PCOS focus on the specific symptoms, with weight loss and lifestyle changes being important.
research Activating Wnt/β-Catenin Signaling Pathway for Disease Therapy: Challenges and Opportunities
Using drugs to activate the Wnt/β-catenin pathway has potential for treating diseases but also presents challenges.