87 citations
,
July 2012 in “Expert Review of Clinical Immunology” This review outlines pregnancy risks in systemic lupus erythematosus and emphasizes that active lupus nephritis at conception increases the risk of flares and poor obstetric outcomes; it reports no new clinical findings.
86 citations
,
June 2018 in “Cochrane library” This review update suggests that mycophenolate mofetil may increase complete disease remission in proliferative lupus nephritis compared to intravenous cyclophosphamide, but with low certainty of evidence.
31 citations
,
July 1975 in “PubMed” This study reported that intensive immunosuppression in multiple sclerosis patients significantly reduced relapse rates versus pre-treatment expectations, though some required ongoing treatment after tapering.
13 citations
,
May 2014 in “PubMed” This study observed that class IV diffuse proliferative glomerulonephritis was the most common form of lupus nephritis among the children studied, with remission achieved in a significant portion after treatment.
12 citations
,
August 2020 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study found that most chronic alopecia areata patients treated with azathioprine, methotrexate, or cyclosporine continued treatment for at least 12 months, often requiring concurrent low-dose prednisolone.
12 citations
,
April 2018 in “Revista Brasileira de Ginecologia e Obstetrícia” This review discusses the prenatal care guidelines for women with systemic lupus erythematosus and emphasizes the need for disease activity control to reduce maternal and fetal complications; it reports no new results.
7 citations
,
July 1990 in “Journal of the American Academy of Dermatology” This case report describes a patient who developed severe alopecia and a rash after increasing captopril dosage, which resolved upon discontinuing the medication.
4 citations
,
January 2024 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This consensus statement outlines a treatment algorithm for alopecia areata, detailing systemic treatment indications and options, including EMA-approved medications baricitinib and ritlecitinib for severe cases, as well as other off-label treatments and adjuvant therapies like oral minoxidil.
3 citations
,
February 2020 in “The Egyptian Rheumatologist” This case report from Tishreen Hospital describes the rare presentation of lupus erythematosus tumidus and autoimmune thyroid dysfunction as initial manifestations of systemic lupus erythematosus, highlighting the importance of early diagnosis for better outcomes.
2 citations
,
October 2022 in “Rheumato” This case report from Tishreen Hospital highlights that although rare, cardiac tamponade and acute surgical abdomen due to acute peritonitis and ascites can occur concurrently as initial presentations of systemic lupus erythematosus.
January 2024 in “Journal der Deutschen Dermatologischen Gesellschaft” This research paper reviews the mechanisms and management of non-biologic immunosuppressive drugs used in dermatology, highlighting their safety profiles and handling during pregnancy, breastfeeding, and vaccination, but does not report specific results on these aspects.
December 2022 in “Gastroenterology” This report describes a case of Cronkhite-Canada syndrome diagnosed in a 54-year-old man with symptoms including gastrointestinal polyps, alopecia, skin hyperpigmentation, and severe diarrhea, who experienced significant symptom improvement with azathioprine.
This case report details a child with a specific TNFAIP3 mutation manifesting as a severe SLE/SS phenotype, expanding the known phenotype for this genetic variant.
May 2018 in “International Journal of Advances in Medicine” This study reports the successful management of acute liver failure in a 25-year-old woman with concurrent Hepatitis B and autoimmune hepatitis, using a combination of steroids, azathioprine, and tenofovir disoproxil fumarate.
65 citations
,
September 2014 in “BMC genomics” This research found that variations in the KRTAP gene family are likely responsible for the diverse hair phenotypes seen among mammals, influenced by gene repertoire differences, expression, and evolutionary factors.
44 citations
,
April 2015 in “PubMed” This study reports that clinical trials of finasteride for androgenic alopecia provide insufficient and systematically biased safety data, with most participants unrepresentative of those in pivotal trials that led to FDA approval.
21 citations
,
January 2016 in “NeuroImmunoModulation” This study found that daily hair washing was associated with significantly lower hair cortisol concentrations, suggesting it may influence the accuracy of using hair cortisol as a biomarker for chronic stress.
13 citations
,
September 2012 in “Critical Reviews in Food Science and Nutrition” This review discusses the functional and nutraceutical importance of wheat straw, emphasizing its bioactive compounds and potential benefits, and reports no new experimental findings.
11 citations
,
May 2022 in “Journal of immunology research” This review characterizes breast implant illness and its autoimmune symptoms, reporting an association between breast implants and autoimmune diseases, with explantation relieving symptoms in over half of patients.
9 citations
,
September 2019 in “Journal of clinical sleep medicine” This study reports a rare case where severe vitamin B12 deficiency was identified as the cause of excessive daytime sleepiness, which resolved after vitamin B12 replenishment.
6 citations
,
August 2008 in “Journal of Paediatrics and Child Health” This case report describes a 5-year-old girl whose undiagnosed Coeliac disease presented with symptoms of alopecia, iron deficiency anemia, and trichobezoar, indicating a link between malabsorption, anemia, and resulting pica.
5 citations
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September 2023 in “Clinical Endocrinology” This study suggests revising PCOS diagnostic criteria to integrate the polymenorrhoea subcategory due to shared metabolic dysfunctions with oligomenorrhoea.
3 citations
,
September 2017 in “Archives of dermatological research” Early diagnosis and tailored treatments are crucial for managing ichthyosis syndromes with hair abnormalities.
3 citations
,
January 2017 in “Journal of Pakistan Association of Dermatology” This study found a significant association between low serum ferritin levels and nonscarring alopecia in women, suggesting the importance of addressing iron deficiency for treatment effectiveness.
3 citations
,
April 2010 in “The FASEB Journal” This study found that estrogen, through estrogen receptors, can regulate the expression of the HOXC13 gene involved in hair follicle development, with MLL3 histone methylase playing a collaborative role.
2 citations
,
September 2020 in “Pakistan Journal of Zoology” This study observed that red sindhi cattle have variations in skin structure between age and sex groups, with more developed skin appendages in adults and a higher density of sweat glands in younger cattle.
1 citations
,
May 2025 in “Discover Chemistry.” This review highlights that although mangiferin, a polyphenol from the mango tree, faces challenges like low solubility and bioavailability, delivery vehicles such as nanoparticles and complexes have the potential to enhance its therapeutic effectiveness in treating various diseases.
1 citations
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February 2024 in “Preprints.org” This review discusses the pharmacology and potential therapeutic effects of rare ginsenoside compound K on metabolic disorders but presents no new clinical results, highlighting the need for further studies on its bioavailability and toxicity.
1 citations
,
September 2023 in “Journal of Fatwa Management and Research” This study identified three main ethical concerns regarding stem cell use from an Islamic perspective in Malaysia, focusing on embryonic stem cells, aesthetic applications, and therapeutic medicine.
1 citations
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January 2018 in “Recent clinical techniques, results, and research in wounds” This review discusses the similarities between wound healing and embryonic development, focusing on signaling pathways and their potential for developing new wound healing strategies, and reports no new clinical results.