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To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

Hormonal therapies are safe and effective for treating adult women's acne.

Hair follicle regeneration possible, more research needed.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

A male with aromatase deficiency improved bone health with estradiol treatment.

Eating disorders can cause skin problems that need treating the underlying condition for better health.

Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

FPHL causes hair loss in women due to genetics and hormones; minoxidil and anti-androgens are treatments, and early intervention is advised.

Minoxidil boosts hair growth by increasing blood flow and nutrients to hair follicles.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

High-intensity interval training improves certain hormone levels and lipid profiles in women with PCOS.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Chemotherapy can cause brain inflammation and damage, and understanding this process could help manage side effects.

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

Dutasteride does not impair mental function in elderly men with enlarged prostate.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.

Obesity is linked to various skin disorders, which can help with early diagnosis and prevention of long-term health issues.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Women with PCOS in North China often have hirsutism and acne, with hirsutism linked to metabolic issues.

Different diagnostic criteria greatly affect PCOS diagnosis rates in teenagers.