research Alopecias in Humans: Biology, Pathomechanisms, and Emerging Therapies
New treatments for hair loss are emerging as we better understand hair growth and its genetic causes.
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research Current and Future Pharmacotherapy for Alopecia Areata
New treatments for hair loss show promise but need more research to confirm safety and effectiveness.
research Dupilumab for Alopecia Areata Treatment: A Double-Edged Sword?
Dupilumab can help hair regrowth but may also trigger alopecia areata.
research Molecular Heterogeneity of Quiescent Melanocyte Stem Cells Revealed by Single-Cell RNA-Sequencing
Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.
research Effectiveness of OR-101, a Next Generation Highly Selective JAK3 Inhibitor, in a Humanized Murine Model of Alopecia Areata
OR-101 shows promise for treating alopecia areata by improving hair growth.
research Efficacy and Safety of Baricitinib in Patients With Alopecia Areata: Evidence to Date
Baricitinib is a promising treatment for alopecia areata.
research Alopecia in COVID-19 Patients: Systematic Review and Meta-Analysis
Different types of hair loss are linked to COVID-19, with some types possibly increasing risk of getting the virus, while others may be triggered or worsened by the virus.
research Biological Effects of Electrical Epilation on Human Hair Follicles and Perifollicular Skin Ex Vivo
Electrical epilation damages hair follicles and surrounding skin, likely preventing hair regrowth.
research Exploring the Role of MicroRNAs in Alopecia Areata
Certain microRNAs may protect against hair loss in alopecia areata and could be potential treatment targets.
research Current Status of Treatments for Alopecia Areata
No cure exists for alopecia areata; treatments aim to manage symptoms.
research Hair Today
The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.
research Hair Development and Langerhans Cell Migration During Human Embryogenesis
Langerhans cells and melanocytes migrate to the skin and hair follicles during early human development.
research Hair Biology and Hair Loss Disorders: An Update and New Concepts
Recent discoveries have improved our understanding of hair loss, but challenges in treatment and knowledge among specialists still exist.
research Rapidly Progressive Alopecia Areata Totalis in a COVID-19 Patient, Unresponsive to Tofacitinib
A COVID-19 patient with severe hair loss did not improve with hair loss medication after stopping and restarting it due to the infection.
research Increased Proliferation of Epidermal Gamma Delta T Cells and Expression of the Transmembrane Protein, BST2, in Alopecia Areata
BST2 protein and certain T cells increase in early alopecia areata.
research Alopecia Areata as a Sequela of Post-Reinfection COVID-19
COVID-19 reinfection may trigger alopecia areata.
research Author Response: Involvement of ILC1-Like Innate Lymphocytes in Human Autoimmunity, Lessons from Alopecia Areata
ILC1-like cells may contribute to hair loss in alopecia areata.
research Decision Letter: Involvement of ILC1-Like Innate Lymphocytes in Human Autoimmunity, Lessons from Alopecia Areata
ILC1-like cells may contribute to hair loss in alopecia areata and could be new treatment targets.
research Herbal Lotions to Regrow Hair in Patients with Intractable Alopecia Areata
Herbal lotions are effective for severe hair loss, with a 64.8% success rate, but relapse is common and long-term management requires allergen control and possible corticosteroid use.
research Neutrophil Elastase Is Critical In Linear IgA Bullous Dermatosis In Mice
CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss.
research Immune-Related Alopecia (Areata and Universalis) in Cancer Patients Receiving Immune Checkpoint Inhibitors
Cancer patients treated with immune checkpoint inhibitors may develop alopecia, but some hair regrowth is possible with treatment.
research Differential Proteomics of Lesional vs. Non-Lesional Biopsies Revealed Non-Immune Mechanisms of Alopecia Areata
Non-immune factors play a significant role in alopecia areata.
research Jagged-1+ Skin Tregs Modulate the Innate Immune Response to Wound Healing
Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.
research Unraveling Vitiligo: From Immune Mechanisms to Promising Therapeutic Strategies
Vitiligo treatments include JAK inhibitors, UVB phototherapy, and dietary changes, with emotional support being important.
research Interrelation of Immunity and Tissue Repair or Regeneration
The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
research Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails
Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.
research Experimental Induction of Alopecia Areata-Like Hair Loss in C3H/HeJ Mice Using Full-Thickness Skin Grafts
Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.
research Regulatory T Cells in Skin: Role of Foxp3+ CD4+ Tregs in Skin Homeostasis and Immune Tolerance
Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
research PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Disturbance of Immune Microenvironment in Androgenetic Alopecia Through Spatial Transcriptomics
Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.