Herbal Lotions to Regrow Hair in Patients with Intractable Alopecia Areata

    Hideo Nakayama, Ko‐Ron Chen
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    TLDR Herbal lotions are effective for severe hair loss, with a 64.8% success rate, but relapse is common and long-term management requires allergen control and possible corticosteroid use.
    The document discusses the use of herbal lotions, such as Laiso®, Fukisin® in Japan, and 101® in China, for treating severe and intractable alopecia areata, including forms like alopecia universalis, totalis, and diffusa. These lotions have been found to be effective, with an average success rate of 64.8% in a study of 54 severe cases. Salvia miltiorrhiza radix (SMR) is identified as the most effective herb for hair growth, but it should not exceed a 2% concentration in lotions due to the risk of contact sensitization. For those who develop sensitization, alternative lotions without SMR are recommended. The study also notes that relapse is common, but maintaining hair growth can be achieved for an average of 4 years by removing allergens that disrupt immune privilege, such as metal and mite allergies. Allergen control, combined with herb lotion application and temporary corticosteroid use, is advised for long-term management.
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