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Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

Activating certain potassium channels in honey bees can lower antioxidant levels and reduce death rates during heavy mite infestations, potentially aiding their immune response.

A Laotian man with unusual skin changes and multiple growths in his gut was diagnosed with Cronkhite-Canada Syndrome and improved with nutritional and immune-based treatments.

UV radiation may cause DNA changes in skin, certain UVB therapy helps psoriasis, a new gene mutation is linked to mild piebaldism, different immune cells affect psoriasis, a drug promotes hair growth, and some cancer drugs could treat skin barrier issues.

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

A new TP63 mutation was found in a baby with EEC syndrome, showing the need for TREC testing to check for immune issues.

The skin produces and uses vitamin D for bone health, cell growth, and immune function.

ANp63 is crucial for skin integrity, new filaggrin gene mutations link to eczema, hair can regrow from non-stem cells, sunburns are increasing, and glucocorticoids help treat skin allergies by affecting immune cells.

Propylthiouracil, a thyroid medication, can cause skin blood clots and immune-related blood vessel inflammation.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Alopecia areata, a common autoimmune hair loss condition, often runs in families.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Alopecia areata is an autoimmune disease where T cells attack hair follicles.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.