106 citations,
March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
99 citations,
June 2005 in “Journal of Cosmetic Dermatology” Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.
97 citations,
September 2006 in “Pharmaceutical Research” No treatment fully prevents hair loss from chemotherapy yet.
89 citations,
September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
79 citations,
September 2018 in “Dermatologic therapy” Oral tofacitinib can significantly improve recalcitrant lichen planopilaris.
71 citations,
January 2019 in “International journal of biological sciences” Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
70 citations,
January 2014 in “International review of cell and molecular biology” Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
68 citations,
March 2008 in “Experimental dermatology” The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
67 citations,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
61 citations,
January 2019 in “American Journal of Clinical Dermatology” The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.
56 citations,
January 2019 in “Lancet” JAK inhibitors help regrow hair in alopecia areata patients, improving their quality of life.
53 citations,
November 1992 in “Mayo Clinic Proceedings” HIV can cause unusual and severe skin problems that are hard to treat.
49 citations,
December 2009 in “Journal of Investigative Dermatology” Thyroid function affects skin health, with a complex interaction between the two.
49 citations,
February 2019 in “The Journal of Clinical Endocrinology and Metabolism” Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.
43 citations,
September 2017 in “Lasers in Surgery and Medicine” LED light therapy may help hair growth by activating certain cell pathways.
43 citations,
March 2011 in “Journal of psychosomatic research” Kids with alopecia areata may experience more stress but not necessarily feel more anxious or depressed than others.
42 citations,
October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
42 citations,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
40 citations,
August 2018 in “Skin appendage disorders” Some alternative treatments for hair loss might work, but more research is needed.
39 citations,
April 2020 in “Clinical, Cosmetic and Investigational Dermatology” Asian hair is generally straight and thick, with unique disorders and properties, and more research is needed to understand it fully.
32 citations,
March 2015 in “The Journal of Clinical Endocrinology & Metabolism” Alopecia areata is linked to thyroid autoimmunity but not type 1 diabetes.
31 citations,
February 2019 in “International Journal of Cosmetic Science” Caffeine applied to the scalp can protect hair follicles from UV damage.
30 citations,
April 2017 in “European Journal of Cell Biology” CIP/KIP proteins help stop cell division and support hair growth.
29 citations,
March 2008 in “Postcolonial Studies” The article concludes that the global hair trade is exploitative and reflects complex cultural and economic issues.
27 citations,
July 2018 in “Journal of optometry” Eyelashes protect the eyes, but more research is needed to understand how.
25 citations,
June 2021 in “Developmental Cell” Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.
25 citations,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
25 citations,
November 2001 in “Kidney International” Male hormones worsen kidney transplant damage, but blocking them helps.
24 citations,
October 2014 in “Cold Spring Harbor Perspectives in Medicine” Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
22 citations,
November 2018 in “Brazilian Journal of Pharmaceutical Sciences” New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.