August 2023 in “Skin Research and Technology” Measuring bald patch size can help grade hair loss severity, with photograph-based evaluation being more reliable.
42 citations,
April 2021 in “JCI insight” Blocking JAK3 signaling can reverse hair loss from alopecia areata.
40 citations,
June 2021 in “Clinical, cosmetic and investigational dermatology” JAK inhibitors show promise in effectively treating hair loss from alopecia areata.
37 citations,
October 2014 in “JAMA dermatology” A woman with severe hair loss was successfully treated with the drug adalimumab.
17 citations,
August 2019 in “Frontiers in Immunology” Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.
11 citations,
November 2021 in “BMJ Open” People with alopecia areata have higher rates of mental health issues, autoimmune diseases, and infections.
5 citations,
December 2021 in “Frontiers in Cell and Developmental Biology” Enzymes called PADIs play a key role in hair growth and loss.
5 citations,
July 2020 in “Recent patents on inflammation & allergy drug discovery” Childhood Alopecia Areata causes hair loss and requires varied treatments, with psychological support being crucial.
3 citations,
April 2022 in “Microorganisms” People with severe hair loss (Alopecia Areata) have different scalp bacteria than healthy people, which might help predict the condition's progress.
3 citations,
September 2021 in “BioEssays” Dandruff might be caused by changes in how hair follicles naturally release oils and an immune response to this imbalance.
1 citations,
August 2023 in “Biomolecules” Certain immune-related proteins are higher in people with alopecia and their healthy relatives, hinting at a genetic link.
1 citations,
January 2020 in “Инфекционные болезни. Новости, мнения, обучение” Lack of vitamin D might cause hair loss due to autoimmune problems, and fixing vitamin D levels could help treat it.
August 2024 in “Frontiers in Pharmacology” Cyclosporine may cause hair loss, so patients need monitoring.
July 2024 in “Journal of Controlled Release” Nanostructured lipid carriers effectively deliver tofacitinib to hair follicles, reversing hair loss in alopecia areata.
April 2024 in “Journal of translational medicine” MJ04, a new compound, effectively promotes hair growth and is a potential topical treatment for hair loss.
December 2023 in “International journal of multidisciplinary research and analysis” SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.
July 2023 in “IntechOpen eBooks” Some types of hair loss can be reversed, others are permanent, and treatments vary by type.
Baricitinib is a new, effective treatment for advanced alopecia areata but is costly and has risks.
January 2023 in “Journal of Cosmetic Dermatology” Some children may develop hair loss after having COVID-19.
November 2022 in “Skin health and disease” People with hair loss conditions often have more mental health issues like depression and anxiety compared to those without hair loss.
April 2018 in “Journal of Investigative Dermatology” Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” N-acetyl-GED may help prevent and partially reverse a process that leads to scarring hair loss.
July 2013 in “Our Dermatology Online” Oral methylprednisolone pulse therapy helped an 11-year-old regrow 80% of his hair in six months.
286 citations,
June 2012 in “Nature Immunology” Hair follicles help attract immune cells to the skin during stress.
119 citations,
December 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Nanoparticles can deliver vaccines through hair follicles, triggering immune responses and providing protection.
45 citations,
August 2018 in “Stem Cells International” Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.
41 citations,
February 2001 in “Current pharmaceutical design” Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.
31 citations,
July 2021 in “ImmunoTargets and therapy” Alopecia areata is an incurable autoimmune condition causing hair loss, with research aiming for better treatments.
28 citations,
March 2010 in “Histochemistry and Cell Biology” Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.
14 citations,
December 2021 in “International journal of molecular sciences” Growth hormone levels affect hair growth and loss, with too much causing excess hair and too little leading to hair loss.