Cyclosporine-Induced Alopecia: A Case Report, FDA Adverse Event Reporting System Analysis and Literature Assessment

This document reports a case of a 29-month-old boy with aplastic anemia who developed alopecia during cyclosporine therapy, which improved after discontinuation of the drug. An analysis of the FDA Adverse Event Reporting System (FAERS) from January 2004 to January 2023 identified 118 cases of cyclosporine-induced alopecia and 197 cases of tacrolimus-induced alopecia. The study highlights a potential correlation between cyclosporine and alopecia, emphasizing the need for clinical monitoring of this adverse effect despite the unclear mechanism.