Upadacitinib for the Treatment of Alopecia Areata and Severe Atopic Dermatitis in a Pediatric Patient: A Case Report

January 2022 in “ SAGE open medical case reports ”

Adrienn N. Bourkas, Cathryn Sibbald

upadacitinib alopecia areata atopic dermatitis Janus kinase 1 inhibitor topical corticosteroids spironolactone

TLDR Upadacitinib successfully treated a child's severe skin and hair loss issues.

This case report details the first successful use of the Janus kinase 1 inhibitor upadacitinib to treat alopecia areata and severe atopic dermatitis in a pediatric patient. The patient showed minimal response to topical corticosteroids and spironolactone, but significant improvements in hair growth on the scalp and body were observed after just 6 weeks of upadacitinib treatment.

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