December 2025 in “Fertility and Sterility” Both LNG-IUD and systemic progestins are effective for fertility-sparing treatment, but close monitoring is needed due to recurrence risk.
22 citations
,
September 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This review highlights the possible role of T regulatory cells in the immune-related mechanisms of alopecia areata but reports no new clinical findings.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that using a commercially available IPL home-use device led to significant hair reduction and demonstrated long-term efficacy in maintaining hair reduction one year after treatment.
11 citations
,
March 2013 in “Gene” This study reported that the IL1A 4-bp indel polymorphism is associated with a reduced risk of alopecia areata in Chinese populations, possibly through miR-122 mediated regulation of IL-1α expression.
11 citations
,
October 2001 in “Dermatologic Clinics” In this study, subcutaneous recombinant human IL-12 showed a 43% partial response rate in early-stage mycosis fungoides patients refractory to previous treatments, with generally mild to moderate adverse events reported.
June 2001 in “Proceedings of SPIE” The authors concluded that low energy laser therapy may serve as a useful complementary treatment for skin diseases such as lichen planus, infectious finger pulpits, scalp alopecia, and crural ulcers.
11 citations
,
January 2020 in “Journal of Drugs in Dermatology” This study found that intralesional triamcinolone acetonide injections effectively increased hair density in African American women with traction alopecia, showing promise as a safe treatment option.
July 2024 in “Journal of Investigative Dermatology” IL-13 protein is much higher in the skin of atopic dermatitis patients than in healthy skin.
10 citations
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January 2007 in “Journal of cosmetic and laser therapy” In this study, a new IPL device effectively reduced hair regrowth with high patient satisfaction, particularly in individuals with coarse dark hair and darker skin, despite repeated sessions needed for lighter hair and skin.
September 2009 in “European Urology Supplements” This study demonstrates that a new Adaptive Modulation and Coding method can improve control performance in Communication-Based Train Control systems using WLAN by reducing average delay through effective transmission mode selection.
3 citations
,
July 2024 in “Journal of Vascular Diseases” This review compiles existing research on ischemia-modified albumin (IMA) as a biomarker for myocardial ischemia, highlighting current gaps in understanding its formation and detection, with no new clinical results reported.
31 citations
,
January 2019 in “Frontiers in Veterinary Science” This study found that low-level laser therapy at 8 J/cm2 improved cosmetic surgical scar healing in canines after thoraco-lumbar hemilaminectomy compared to controls.
26 citations
,
September 2023 in “Journal of Allergy and Clinical Immunology” Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.
20 citations
,
January 2023 in “Frontiers in Immunology” This review discusses the role of skin-associated adipocytes in modulating skin immune responses and infection, reporting no new experimental results.
16 citations
,
June 2018 in “JAAD case reports” This article reviews the differences in inflammatory processes between alopecia universalis and atopic dermatitis, focusing on type 1 and type 2 immune responses, but it reports no new results.
4 citations
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December 2024 in “Archives of Dermatological Research” May 2025 in “International Journal of Trichology” This case report highlights a 7-year-old boy with suspected Netherton syndrome who presented with itchy lesions, hair abnormalities, and elevated immunoglobulin E levels. The authors report complete resolution of symptoms with oral Acitretin after failed methotrexate treatment.
July 2021 in “The Egyptian Journal of Hospital Medicine” This study observed that intralesional Triamcinolone acetonide injections were generally safe and effective for alopecia areata, with most patients experiencing good hair growth responses, though side effects like pain and atrophy were noted.
September 2022 in “International Journal of Trichology” In this study, microneedling and intralesional corticosteroid injections in patients with alopecia areata showed similar hair regrowth effectiveness, with microneedling resulting in more uniform but less dense regrowth and fewer side effects.
28 citations
,
December 2018 in “Plant, cell & environment/Plant, cell and environment” This study found that the PLC2 gene plays a critical role in auxin-mediated root development in Arabidopsis, influencing root growth and PIN2 distribution.
This study found a direct correlation between IL6 and insulin, glucose, and cholesterol serum levels in patients with oral lichen planus, suggesting a potential increased cardiovascular risk.
10 citations
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July 2021 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin” This study found that the expression of LRIG1 in Merkel cell carcinoma tumors was associated with improved overall and cancer-specific survival.
April 2017 in “Journal of Investigative Dermatology” In this pilot study, researchers observed a correlation between clinical severity and histologic severity of lichen planopilaris, suggesting that an immunohistochemical scoring system could aid in grading disease activity.
37 citations
,
April 2018 in “Journal of Allergy and Clinical Immunology” This study found that a novel IKZF1 mutation, p.L188V, is linked to juvenile-onset systemic lupus erythematosus and alters B-cell activation by disrupting normal DNA binding.
323 citations
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November 2017 in “Bioanalysis” This commentary discusses the challenges of matrix effects in LC–MS analysis and introduces the concept of a matrix effect factor using stable isotopically labeled internal standards to improve analysis reliability.
April 2010 in “Cancer Research” This study found significant upregulation of IDO-1 and IDO-2 in human basal cell carcinomas, suggesting that IDO production may confer immune privilege characteristics to the tumors, potentially impacting their growth.
In this case study, a patient with refractory oral lichen planus experienced marked improvement within one month of daily treatment with baricitinib, contributing to the evidence supporting the use of JAK inhibitors for lichen planus.
6 citations
,
August 2016 in “Journal of Visualized Experiments” This article describes a method using the CUBIC protocol to clarify and visualize molecular and cellular interactions in mouse skin biopsies at single cell resolution, but does not provide new biological findings.
November 2025 in “The Journal of Immunology” In a murine model of alopecia areata, this study observed that the IL-2 fusion protein HCW9302 helped prevent disease development by expanding regulatory T cells and reducing disease-causing effector T cell infiltrates, suggesting potential for using IL-2 fusion proteins in alopecia areata treatment.