Skin-Associated Adipocytes in Skin Barrier Immunity: A Mini-Review
January 2023
in “
Frontiers in Immunology
”
TLDR Skin-associated adipocytes help protect the skin from infections by supporting its immune barrier.
This mini-review highlights the crucial role of skin-associated adipocytes in maintaining skin barrier immunity. These adipocytes contribute to the skin's defense against external pathogens by secreting cytokines, adipokines, and antimicrobial peptides, which modulate immune responses and infections. The review emphasizes the importance of the interaction between skin-associated adipocytes and other skin cells in preserving the integrity and effectiveness of the skin's barrier function.