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The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

The document explains various skin conditions and their treatments.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Hirsutism, excessive hair growth in women, is often caused by PCOS and can be managed with medication and personalized treatment plans.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

Women with excessive male-pattern hair growth should get a full hormone check-up to find and treat any underlying issues, considering both medical and emotional aspects.

PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.

Pea sprout extract is safe and effectively reduces hair loss.

North American ginseng extract helped regrow hair in balding mice.

Mice treatments didn't grow hair, a patient treatment may affect immune response, and people with hair loss often feel anxious or depressed.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

The document concludes that freeze-dried platelet-rich plasma shows promise for medical use but requires standardization and further research.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

An 81-year-old man's white hair began to regain its original color while he was treated with lenalidomide, suggesting that graying hair might be reversible.

Some herbal treatments are effective for skin disorders, but more research and regulation are needed.