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30 / 389 resultsresearch Regulation of human dermal papilla cell production of insulin-like growth factor binding protein-3 by retinoic acid, glucocorticoids, and insulin-like growth factor-1
Retinoic acid, glucocorticoids, and IGF1 increase IGFBP-3 production in human dermal papilla cells, affecting hair growth.
![Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3](/images/research/1cf4082f-6cd5-4e75-b288-ec2c9fe2e0e1/small/20496.jpg)
research Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3
Men with balding at age 45 had higher IGF-1 and lower IGFBP-3, suggesting these factors might be important in male pattern baldness.
![Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3](/images/research/9f979bb6-9add-4ce7-813f-9381455a9bd9/small/20500.jpg)
research Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3
Men with balding at age 45 had higher IGF-1 and lower IGFBP-3 levels, suggesting these factors might influence male pattern baldness.
![<scp>IGFBP‐rP1</scp> is a potential therapeutic target in androgenic alopecia](/images/research/f620b95e-2f08-4aef-b568-e4a7836bacb3/small/26424.jpg)
research IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia
IGFBP-rP1 could be a new treatment for a common type of hair loss.
![β-catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair](/images/research/f22ee802-ae0e-43cf-84ca-3528bdd5f498/small/19905.jpg)
research β-catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair
β-catenin in the dermal papilla is crucial for normal hair growth and repair.
![The Molecular Mechanism Underlying the Proliferating and Preconditioning Effect of Vitamin C on Adipose-Derived Stem Cells](/images/research/e5f0bb7e-4110-45f3-b9a4-def712250d7c/small/23095.jpg)
research The Molecular Mechanism Underlying the Proliferating and Preconditioning Effect of Vitamin C on Adipose-Derived Stem Cells
Vitamin C helps adipose-derived stem cells grow and may support hair growth.
![Insulin-like growth factor-1: roles in androgenetic alopecia](/images/research/d2b0daf2-dbbb-44c7-81c7-17e526a3ac18/small/3425.jpg)
research Insulin-like growth factor-1: roles in androgenetic alopecia
IGF-1 affects hair loss and could be a potential treatment.
![Effects of Short-Term Finasteride on Apoptotic Factors and Androgen Receptors in Prostate Cancer Cells](/images/research/a3e58ae3-b0e0-40fa-8f59-49639a4af64d/small/14952.jpg)
research Effects of Short-Term Finasteride on Apoptotic Factors and Androgen Receptors in Prostate Cancer Cells
Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.
![Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth](/images/research/91a883e7-20d1-4017-a428-698de46f3ca3/small/13598.jpg)
research Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth
Modified stem cells from umbilical cord blood can make hair grow faster.
![Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts](/images/research/0a911e80-06f7-4b90-9c58-7d9b86848b71/small/33312.jpg)
research Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts
Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.
![Conditioned media obtained from human outer root sheath follicular keratinocyte culture activates signalling pathways that contribute to maintenance of hair-inducing capacity and increases trichogenicity of cultured dermal cells](/images/research/740538cd-e49a-4745-b913-cf8233618691/small/12853.jpg)
research Conditioned media obtained from human outer root sheath follicular keratinocyte culture activates signalling pathways that contribute to maintenance of hair-inducing capacity and increases trichogenicity of cultured dermal cells
The substance from human hair root cells can help maintain hair growth and make skin cells more capable of growing hair.
![Concentrated Conditioned Medium-Loaded Silk Nanofiber Hydrogels with Sustained Release of Bioactive Factors To Improve Skin Regeneration](/images/research/6f622a63-4f40-4610-889d-78e47b67343a/small/19328.jpg)
research Concentrated Conditioned Medium-Loaded Silk Nanofiber Hydrogels with Sustained Release of Bioactive Factors To Improve Skin Regeneration
The hydrogel with bioactive factors improves skin healing and regeneration.
![Skin Deep and Deeper: Multiple Pathways in Basal Cell Carcinogenesis](/images/research/57d462ae-bdbe-42b7-8cbb-fa2655e373ac/small/19899.jpg)
research Skin Deep and Deeper: Multiple Pathways in Basal Cell Carcinogenesis
The research suggests new treatments for skin cancer could target specific cell growth pathways.
![Bald thigh syndrome in sighthounds—Revisiting the cause of a well-known disease](/images/research/9233373c-9b2d-4ea1-9f61-dad7576d83f6/small/29036.jpg)
research Bald thigh syndrome in sighthounds—Revisiting the cause of a well-known disease
Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.
![Australian Hair and Wool Research Society Cutaneous Biology and Endocrinology Workshop](/images/research/34d6bc7b-ec89-4d03-b452-21cab736016e/small/23458.jpg)
research Australian Hair and Wool Research Society Cutaneous Biology and Endocrinology Workshop
The workshop highlighted the genetic links and psychological impacts of hair loss and skin disorders.
![L-(+)-Tartaric Acid Minimally Affects the Viability or Molecular Signature but Increase the Expression of Selected Hair Growth Associated Genes in Human Dermal Papilla Cells](/images/research/55ca22ba-08c4-4896-a00e-8badf5d53b52/small/15795.jpg)
research L-(+)-Tartaric Acid Minimally Affects the Viability or Molecular Signature but Increase the Expression of Selected Hair Growth Associated Genes in Human Dermal Papilla Cells
L-(+)-Tartaric Acid may help increase certain hair growth genes without harming cells.
![Distinct tooth regeneration systems deploy a conserved battery of genes](/images/research/9a145602-903f-4ed7-9f83-f6784488ed41/small/36939.jpg)
research Distinct tooth regeneration systems deploy a conserved battery of genes
Different fish use the same genes to regrow teeth.
research Distinct tooth regeneration systems deploy a conserved battery of genes
Different species use the same genes for tooth regeneration.
![Prevalence of polycystic ovaries in women with self-reported symptoms of oligomenorrhoea and/or hirsutism: Northern Finland Birth Cohort 1966 Study](/images/research/261c8519-7a68-4115-bbfe-a55823eefab8/small/15342.jpg)
research Prevalence of polycystic ovaries in women with self-reported symptoms of oligomenorrhoea and/or hirsutism: Northern Finland Birth Cohort 1966 Study
Women with irregular periods and/or excessive body hair are more likely to have polycystic ovaries, and this condition is linked to higher health risks.
![(Neuro-)endocrinology of epithelial hair follicle stem cells](/images/research/9f993e96-6c55-42a5-9501-05dc462b0eed/small/24831.jpg)
research (Neuro-)endocrinology of epithelial hair follicle stem cells
Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
![Hair-Growth-Promoting Effect of Conditioned Medium of High Integrin α6 and Low CD 71 (α6bri/CD71dim) Positive Keratinocyte Cells](/images/research/185396fb-8a6d-46af-a21e-16aa245cad5e/small/23074.jpg)
research Hair-Growth-Promoting Effect of Conditioned Medium of High Integrin α6 and Low CD 71 (α6bri/CD71dim) Positive Keratinocyte Cells
A special mix from certain skin cells can help hair grow by making hair root cells grow faster and activating growth signals.
![Promoting longevity: A global approach](/images/research/063955ce-9895-4736-aea4-e4e93812c8b1/small/16056.jpg)
research Promoting longevity: A global approach
The document concludes that managing health issues like menopause, cardiovascular risk, and hair loss is crucial for promoting longevity in aging women.
![Metformin or Antiandrogen in the Treatment of Hirsutism in Polycystic Ovary Syndrome](/images/research/7689fab4-6a3d-4c37-8f87-98ca76ffe804/small/28155.jpg)
research Metformin or Antiandrogen in the Treatment of Hirsutism in Polycystic Ovary Syndrome
Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.
![Wnt signaling in skin organogenesis](/images/research/c9682199-6fa1-4b40-a60d-892f0165f036/small/19958.jpg)
research Wnt signaling in skin organogenesis
Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
![Use of Insulin-Sensitizing Agents in Patients With Polycystic Ovary Syndrome](/images/research/ad79d13d-6cb5-4117-8721-7757c9e3be4a/small/15483.jpg)
research Use of Insulin-Sensitizing Agents in Patients With Polycystic Ovary Syndrome
Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.
![The effect of cilostazol, a phosphodiesterase 3 (PDE3) inhibitor, on human hair growth with the dual promoting mechanisms](/images/research/10f13cec-7a41-48b7-8a2a-031e9f5426f5/small/22972.jpg)
research The effect of cilostazol, a phosphodiesterase 3 (PDE3) inhibitor, on human hair growth with the dual promoting mechanisms
Cilostazol helps hair grow by making hair root cells grow faster and changing growth factor levels.
![Polygonum multiflorum extract support hair growth by elongating anagen phase and abrogating the effect of androgen in cultured human dermal papilla cells](/images/research/7f6c1c7d-5020-437b-a6f1-8e48f57790ff/small/13303.jpg)
research Polygonum multiflorum extract support hair growth by elongating anagen phase and abrogating the effect of androgen in cultured human dermal papilla cells
Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.
![Hyperandrogenism in Adolescent Girls](/images/research/29ccdec2-1f52-45b1-b06e-8e0863aab64c/small/14636.jpg)
research Hyperandrogenism in Adolescent Girls
The conclusion is that a thorough approach is needed to diagnose and manage hyperandrogenism in teenage girls, recognizing its major psychological and health effects.
![Comparison between single- versus double-spin prepared platelet-rich plasma injection in treatment of female pattern hair loss: clinical effect and relation to vascular endothelial growth factor](/images/research/d35bf1ee-659a-4940-aa85-96452feb2dea/small/5335.jpg)
research Comparison between single- versus double-spin prepared platelet-rich plasma injection in treatment of female pattern hair loss: clinical effect and relation to vascular endothelial growth factor
Both methods improve hair density and thickness; double-spin may be more effective.