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Keratins are crucial for cell structure, growth, and disease risk.

This article reviews recent advancements in understanding skin stem cells and their roles in maintaining epidermal homeostasis and repairing wounds, without presenting new experimental findings.

This review discusses the role of keratins in maintaining epidermal structure and function and reports no new results; the authors emphasize the lack of rational therapies for skin disorders linked to keratin mutations.

This study observed that genetic variation in the ovine KRTAP22-1 gene is linked to increased wool yield and decreased fiber curvature in sheep, indicating its potential use in breeding programs.

This study found that the mechanical stiffening of the human hair follicle along the first millimeter is linked to changes in the keratin network architecture and composition during keratinization.

This study found that hair loss is common following metabolic and bariatric surgery, particularly among younger women with low serum levels of zinc, folic acid, and ferritin.

This research examined the ultrastructure of deer hair fibers and found significant variations in diameter, cuticle thickness, and intermediate filament arrangements among different fiber types.

This study presents computational modeling and experimental analysis of the HGT protein KAP8.1, identifying key structural features that may influence hair's response to environmental conditions.

This study demonstrated that molecular dynamics simulations of keratin could effectively model the mechanical properties of hair, aligning well with experimental data, especially when conducted in vacuum conditions.

This review covers various aspects of hair biology, pigmentation, and development, focusing on genetic and biochemical modulation of hair follicle components but reports no new findings.

This study found that bleached hair showed optimal protein structural integrity and tensile strength at pH 5, with significant changes in cross-linking, water content, and diameter at more alkaline or acidic levels.

This study proposed the existence of a membrane-like structure between the cuticle and cortex in human hair, which may provide strong protection against external stimuli.

This study reported that using 2D solid-state NMR techniques on extensively labeled mouse fur improves resolution in detecting chemical shifts and secondary structure features, potentially aiding the analysis of the effects of commercial or therapeutic treatments on specific amino acids.

This study identified molecular elements controlling the expression and stabilization of THH protein in hair follicle cells, revealing key mechanisms that support hair shaft development in mice.

This study re-analyzed single-cell RNAseq data from human and mouse skin, confirming and refining insights into keratin gene regulation during keratinocyte differentiation in epithelial tissues.

In a study using a placebo-controlled design, the researchers found that coenzyme Q10 may enhance gene expression of age-relevant hair keratins in human hair roots, suggesting potential anti-aging benefits for mature hair.

In this study, the bending stiffness of human hair was linked to the varying proportions of para-like versus ortho-like cortical cells within the hair fiber.

This study proposed a network model for the cross-linked structure of keratin-associated proteins in hair and wool fibers, suggesting notable differences between the two, potentially affecting hair fiber elasticity.

This study re-analyzed single cell RNAseq data and confirmed longstanding views on keratin gene regulation in keratinocytes, while challenging assumptions about their role in cellular differentiation states.

In this study, researchers found that the expression of vimentin, desmin, and laminin in rat skin contributes to cell structure and tissue integrity, with varying reactions across different cell types.

This article presents a comprehensive guide for classifying human hair follicle cycle stages in vivo using scalp xenografts on immunocompromised mice, offering valuable resources for researchers in the field.

This review discusses recent advances in skin penetration mechanisms, specifically focusing on the enhanced understanding of the follicular pathway and its implications for transdermal therapies, immune system targeting, and nanoparticle safety.

This review discusses advances in understanding hair and hair follicle structure, gene expression, and molecular signals in hair formation, without reporting new clinical findings.

Diffuse alopecia in women may be related to androgens and iron deficiency, and basic hormone and nutrient screening is useful.

This study found that K17 is crucial for the structural integrity and survival of hair-producing cells, with K17 null mice developing alopecia due to hair fragility and follicular alterations.

This review explores the biology of wool follicles and suggests their potential use as research models in modern biology, but it reports no new findings.

This article proposes an updated naming system for keratin-associated proteins and genes, aiming to improve data storage and retrieval by including species information and genetic variation.

This review examines dandruff and seborrheic dermatitis, highlighting the role of Malassezia yeasts in inflammation and hyper-proliferation, and reports no new clinical findings.

This study found that beard hair medulla cells express an unexpected range of keratins, showing variability and promiscuous behavior in keratin interactions distinct from other hair follicle cells.

This study suggests that the GPX-PDE1 and GPX-PDE2 genes in white lupin enhance root hair development and contribute to Pi limitation acclimation by facilitating glycerophosphodiester degradation.