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This open-label study suggests that combining valproate, lamotrigine, and a benzodiazepine can significantly reduce the frequency of epileptic drop attacks in patients with generalized or multifocal epilepsies.

This study found that abietic acid from pine resin more effectively inhibits testosterone 5α-reductase than several plant extracts, suggesting potential for treating androgen-dependent diseases.

This study found that drying finasteride solvates at 85 °C for one day produced a metastable anhydrous form.

This study utilized magnetic resonance imaging to noninvasively visualize and differentiate skin structures in rat skin, finding a significant correlation between MRI data and histological areas.

New, cheaper method measures finasteride in tablets accurately and quickly.

This study found that the spinal projection of afferents innervating slowly adapting mechanoreceptors had a greater rostrocaudal extent and number of boutons compared to those innervating rapidly adapting mechanoreceptors.

This review examines the cognitive effects of medications for lower urinary tract symptoms and indicates that muscarinic antagonists, particularly oral oxybutynin, pose the highest risk for cognitive impairment.

This study found that long-term dutasteride therapy in men with benign prostatic hyperplasia worsened erectile dysfunction, reduced testosterone levels, and increased blood glucose and lipid profile, indicating negative metabolic impacts.

This study reports that five new progesterone derivatives demonstrated inhibitory activity against the 5α-reductase enzyme and binding affinity for the androgen receptor in an in vitro hamster model.

This study found that using a ruby laser for hair removal resulted in a significant average reduction of 56.4% in hair density among participants dissatisfied with other methods.

This study reported that newly synthesized phenanthridin-3-one derivatives effectively inhibit human steroid 5-α-reductase.

This review explores the diverse roles of rosemary, covering its nutritional and medicinal uses, cosmetic and pharmaceutical applications, and evaluates various extraction methods, with a focus on sustainable practices and commercial prospects.

This study found that adipose-derived stem cell exosomes promoted hair follicle regeneration in mice, resulting in a higher number of regenerated hairs and follicles compared to the control group.

This study found that nano-sized minoxidil formulations significantly increased skin penetration and follicular drug delivery for alopecia areata treatment, compared to conventional ethanol-based solutions, and demonstrated effective controlled release over six hours.

In this study, researchers measured that the MMP drug delivery technique administered approximately 1,175 μg/cm² of medication into the dermis of human skin, but these findings are specific to the experimental protocol used.

This research investigated aqueous alginate-based hydrogels for delivering minoxidil and reported that using hydroxypropyl-β-cyclodextrin (HP-β-CD) with molar substitution 0.65 significantly enhanced minoxidil's solubility and skin permeability without damaging the epidermis, suggesting potential as an alternative to commercial minoxidil solutions.

This study found that proteins secreted by early-passage dermal papilla cells, including SDF1, MMP3, biglycan, and LTBP1, may play significant roles in hair follicle regeneration.

This study found that the methanolic heartwood extract of Avicennia marina significantly inhibits 5α-reductase type 1, reducing 5α-DHT production by 52% in a cell-based assay with human hair dermal papilla cells.

This study found that disrupting the inturned gene in developing mouse epidermis halted hair follicle formation due to impaired keratinocyte differentiation, highlighting primary cilia's role in tissue-specific planar cell polarity signaling.

This review discusses the topical use of systemic drugs for cutaneous disorders and reports a lack of strong evidence from randomized controlled trials, highlighting the need for larger comparative effectiveness studies.

This review discusses various aspects of unwanted facial hair, including its psychological impact and current treatment options, and reports no new clinical results from the satellite symposium at the EHRS Meeting.

This review discusses the relationship between zinc deficiency and skin disorders, emphasizing zinc transporters' roles, but it reports no new clinical results; the authors highlight potential benefits of regulating zinc levels via transporters.

This study analyzed gene expression changes during the autumn coat color change in mountain hares and found conserved gene regulation with snowshoe hares, highlighting its role in seasonal camouflage adaptation.

This study observed that electro-acupuncture reduced global DNA methylation and DNMT3b expression in a PCOS-like rat model, suggesting a role of hypothalamic DNA methylation in PCOS development and treatment.

This study evaluated new aqueous gel formulations of minoxidil without irritants and found that the calcium alginate gel showed the best performance in terms of drug release and skin permeation.

This study introduces a new multimodal imaging technology to visualize and quantify cell dynamics in natural skin over long durations, demonstrated in GFP bone marrow-transplanted mice, to study dynamic skin regeneration.

This study found that several new pregnane derivatives, especially steroids 16 and 19, demonstrated higher antiandrogenic activity on male hamster models than the commonly used finasteride.

This study identified the N-(iodopropenyl) derivative 13 as a promising candidate for development as a radioiodinated androgen receptor ligand due to its binding affinity.

This study isolated new geranylated coumarins from Mammea siamensis flowers and found that several of these compounds inhibit testosterone 5α-reductase.

This study found that despite carrying an activating Hras mutation, hair follicle stem cells integrate into normal skin without causing tumors, unlike similar mutations in the epidermis, suggesting unique tumor-suppressing mechanisms in hair follicles.