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Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Oestrogens are key for bone growth during puberty in both boys and girls.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

Some common medications can harm male fertility, but many effects can be reversed.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.

Treating early puberty with hormone therapy may increase the risk of polycystic ovary syndrome in adults.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

Father's finasteride use may affect son's fertility and testicular function.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.